ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	BARX2
Approved Name	BARX homeobox 2
Previous Name	BarH-like homeobox 2
Location	11q24.3
Position	chr11:129245835-129322174, +
External Links	HGNC: 956 Entrez Gene: 8538 Ensembl: ENSG00000043039 UCSC: uc001qfc.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 11)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0001502	cartilage condensation	Biological Process		5
GO:0003677	DNA binding	Molecular Function	IDA[10854790]	220
GO:0003682	chromatin binding	Molecular Function		48
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function		132
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process		78
GO:0000976	transcription regulatory region sequence-specific DNA binding	Molecular Function		4
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process		131
GO:0005667	transcription factor complex	Cellular Component		51
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0014902	myotube differentiation	Biological Process		2
GO:0042637	catagen	Biological Process		1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with BARX2 (count: 15)

Gene Symbol	Pathway Count	Pathway List
MYB	6	DNA binding; chromatin binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent;
SREBF1	6	DNA binding; chromatin binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent;
KDM1A	6	chromatin binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex; transcription, DNA-dependent;
E2F5	5	DNA binding; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex; transcription, DNA-dependent;
E2F6	5	DNA binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; transcription factor complex; transcription, DNA-dependent;
ETS1	5	DNA binding; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex; transcription, DNA-dependent;
FOXE1	5	DNA binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex;
HNF1B	5	DNA binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex;
IKZF1	5	DNA binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent;
NPAS2	5	DNA binding; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex; transcription, DNA-dependent;
RCOR2	5	DNA binding; chromatin binding; sequence-specific DNA binding transcription factor activity; transcription factor complex; transcription, DNA-dependent;
RELA	5	DNA binding; chromatin binding; sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex;
GATA6	5	chromatin binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex;
MTA2	5	chromatin binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription factor complex;
NCOR1	5	chromatin binding; sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; transcription factor complex; transcription, DNA-dependent;

Genes shared at least 2 KEGG pathways with BARX2 (count: 0)

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Region: chr11:129245835..129322174 View in gBrowse