ADHDgene Database

Gene Report

Basic Info

Approved Symbol	E2F6
Symbol Alias	E2F-6
Approved Name	E2F transcription factor 6
Location	2p25.1
Position	chr2:11584501-11606297, -
External Links	HGNC: 3120 Entrez Gene: 1876 Ensembl: ENSG00000169016 UCSC: uc002rbh.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
2p25.1	chr2:7100000-12200000	2 (1/0/1)

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0071339	MLL1 complex	Cellular Component	IDA[15960975]	7
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0005667	transcription factor complex	Cellular Component		51
GO:0003714	transcription corepressor activity	Molecular Function	TAS[9501179]	29
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function		132
GO:0003677	DNA binding	Molecular Function		220
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	TAS[9501179]	78
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	Biological Process		7

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with E2F6 (count: 4)

Gene Symbol	Pathway Count	Pathway List
BARX2	5	transcription, DNA-dependent; transcription factor complex; sequence-specific DNA binding transcription factor activity; DNA binding; negative regulation of transcription from RNA polymerase II promoter;
DRAP1	5	transcription, DNA-dependent; transcription corepressor activity; sequence-specific DNA binding transcription factor activity; DNA binding; negative regulation of transcription from RNA polymerase II promoter;
NCOR1	5	transcription, DNA-dependent; transcription factor complex; transcription corepressor activity; sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter;
RCOR2	5	transcription, DNA-dependent; transcription factor complex; transcription corepressor activity; sequence-specific DNA binding transcription factor activity; DNA binding;

Genes shared at least 2 KEGG pathways with E2F6 (count: 0)

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Region: chr2:11584501..11606297 View in gBrowse