ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa04620
Name Toll-like receptor signaling pathway
No. of Genes in ADHDgene  14
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 14)

Literature-origin genes (count: 1)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
MAP2K3 mitogen-activated protein kinase kinase 3 17q11.2 1(0/1/0)

Genes from other sources Help(count: 13)

Approved Symbol Approved Name Location Source
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 5q31.1-q33.1 Mapped by significant region
MAPK3 mitogen-activated protein kinase 3 16p11.2 Mapped by CNV
FADD Fas (TNFRSF6)-associated via death domain 11q13.3 Mapped by significant region
IL6 interleukin 6 (interferon, beta 2) 7p21-p15 Mapped by significant region
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 11q13 Mapped by significant region
MAPK9 mitogen-activated protein kinase 9 5q35 Mapped by CNV
MAPK1 mitogen-activated protein kinase 1 22q11.2 Mapped by LD-proxy
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 11q24.2 Mapped by significant region
TLR4 toll-like receptor 4 9q33.1 Mapped by significant region
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7q22 Mapped by CNV
IRF7 interferon regulatory factor 7 11p15.5 Mapped by LD-proxy
TLR9 toll-like receptor 9 3p21.3 Mapped by LD-proxy
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 Mapped by significant region