ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007173
Name epidermal growth factor receptor signaling pathway
Type biological process
No. of Genes in ADHDgene  32
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 32)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0) TAS
ADRBK1 adrenergic, beta, receptor kinase 1 11q13 1(0/1/0) TAS
EREG epiregulin 4q21.21 1(0/0/1) ISS

Genes from other sources Help (count: 29)

Approved Symbol Approved Name Source Evidence[PMID]
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) Mapped by significant region TAS
BAD BCL2-associated agonist of cell death Mapped by significant region TAS
MAPKAP1 mitogen-activated protein kinase associated protein 1 Mapped by significant region TAS
PDPK1 3-phosphoinositide dependent protein kinase-1 Mapped by significant region TAS
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase Mapped by significant region TAS
ADCY4 adenylate cyclase 4 Mapped by significant region TAS
ADCY9 adenylate cyclase 9 Mapped by significant region TAS
REPS2 RALBP1 associated Eps domain containing 2 Mapped by CNV TAS[9422736]
GAREM GRB2 associated, regulator of MAPK1 Mapped by significant region IDA[19509291]
RICTOR RPTOR independent companion of MTOR, complex 2 Mapped by significant region TAS
VIL1 villin 1 Mapped by significant region IDA[17229814]
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 Mapped by CNV TAS
BCAR1 breast cancer anti-estrogen resistance 1 Mapped by significant region ISS
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 Mapped by significant region TAS
NCK2 NCK adaptor protein 2 Mapped by PBA pathway TAS[9737977]
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 Mapped by Literature SNP TAS
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy TAS
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta Mapped by CNV TAS
ADCY2 adenylate cyclase 2 (brain) Mapped by significant region TAS
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 Mapped by significant region TAS[8808684]
ERBB2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 Mapped by LD-proxy NAS[15504738]
ADAM17 ADAM metallopeptidase domain 17 Mapped by significant region IDA[12743035]; TAS
UBC ubiquitin C Mapped by CNV TAS
UBB ubiquitin B Mapped by significant region TAS
PLCE1 phospholipase C, epsilon 1 Mapped by PBA pathway NAS[11022048]
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Mapped by significant region TAS
TSC2 tuberous sclerosis 2 Mapped by significant region TAS
ADCY3 adenylate cyclase 3 Mapped by LD-proxy TAS
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV TAS