ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007254
Name JNK cascade
Type biological process
No. of Genes in ADHDgene  12
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 12)

Literature-origin genes (count: 1)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
FGF12 fibroblast growth factor 12 3q28 1(0/1/0) IPI[12815063]

Genes from other sources Help (count: 11)

Approved Symbol Approved Name Source Evidence[PMID]
PTGER4 prostaglandin E receptor 4 (subtype EP4) Mapped by significant region ISS
DUSP12 dual specificity phosphatase 12 Mapped by CNV IRD
UBC ubiquitin C Mapped by CNV TAS
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 Mapped by significant region TAS[7477268]
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like Mapped by CNV TAS[8798523]
UBB ubiquitin B Mapped by significant region TAS
MAP3K11 mitogen-activated protein kinase kinase kinase 11 Mapped by significant region TAS[10799501]
ROR2 receptor tyrosine kinase-like orphan receptor 2 Mapped by significant region IEA
MAPK9 mitogen-activated protein kinase 9 Mapped by CNV IDA[8654373]; TAS
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5 Mapped by PBA pathway IEA
MAP3K5 mitogen-activated protein kinase kinase kinase 5 Mapped by LD-proxy; Mapped by significant region IDA