ADHDgene Database

Gene Report

Basic Info

Approved Symbol	DUSP12
Symbol Alias	YVH1, DUSP1
Approved Name	dual specificity phosphatase 12
Name Alias	serine/threonine specific protein phosphatase, "YVH1 protein-tyrosine phosphatase (S. cerevisiae) ortholog"
Location	1q21-q22
Position	chr1:161719548-161727028, +
External Links	HGNC: 3067 Entrez Gene: 11266 Ensembl: ENSG00000081721 UCSC: uc001gbo.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_17	chr1:159732044-160485312 (NCBI Build 36.1 (hg18))	701326	1q23.3	Loss

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005634	nucleus	Cellular Component		770
GO:0005737	cytoplasm	Cellular Component		690
GO:0004725	protein tyrosine phosphatase activity	Molecular Function		19
GO:0007254	JNK cascade	Biological Process		11
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	Molecular Function		8
GO:0006464	cellular protein modification process	Biological Process	TAS[10446167]	13
GO:0006470	protein dephosphorylation	Biological Process		18
GO:0035335	peptidyl-tyrosine dephosphorylation	Biological Process	TAS[10446167]	11
GO:0033133	positive regulation of glucokinase activity	Biological Process		2
GO:0019900	kinase binding	Molecular Function		7
GO:0008270	zinc ion binding	Molecular Function		323

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DUSP12 (count: 4)

Gene Symbol	Pathway Count	Pathway List
CDC14B	5	nucleus; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; protein dephosphorylation; peptidyl-tyrosine dephosphorylation;
MTMR2	5	nucleus; cytoplasm; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; protein dephosphorylation;
PTPN14	5	nucleus; cytoplasm; protein tyrosine phosphatase activity; protein dephosphorylation; peptidyl-tyrosine dephosphorylation;
SSH3	5	nucleus; cytoplasm; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; protein dephosphorylation;

Genes shared at least 2 KEGG pathways with DUSP12 (count: 0)

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Region: chr1:161719548..161727028 View in gBrowse