ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007179
Name transforming growth factor beta receptor signaling pathway
Type biological process
No. of Genes in ADHDgene  13
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 13)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
XPO1 exportin 1 2p15 1(0/0/1) TAS
FURIN furin (paired basic amino acid cleaving enzyme) 15q26.1 1(0/0/1) TAS
ARRB2 arrestin, beta 2 17p13 1(1/0/0) IDA[12958365]

Genes from other sources Help (count: 10)

Approved Symbol Approved Name Source Evidence[PMID]
LTBP3 latent transforming growth factor beta binding protein 3 Mapped by significant region IEA
MEN1 multiple endocrine neoplasia I Mapped by significant region TAS
UBB ubiquitin B Mapped by significant region TAS
NCOR2 nuclear receptor corepressor 2 Mapped by CNV TAS
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase Mapped by significant region TAS
PTPRK protein tyrosine phosphatase, receptor type, K Mapped by CNV; Mapped by significant region IDA[15899872]
TGFBR1 transforming growth factor, beta receptor 1 Mapped by significant region IC[1326540]; IDA[9389648]; IMP[1333888]; TAS
UBC ubiquitin C Mapped by CNV TAS
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme Mapped by significant region TAS
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase Mapped by significant region TAS