ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0010628
Name positive regulation of gene expression
Type biological process
No. of Genes in ADHDgene  29
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 29)

Literature-origin genes (count: 10)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 1(1/0/0) ISS
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 22q11.22 1(0/0/1) IMP
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 10q21 2(0/2/0) ISS[18180363]
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 9q21.32 1(1/0/0) IMP[15006356]
NFIL3 nuclear factor, interleukin 3 regulated 9q22 2(1/1/0) IEA
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0) IDA[18386220]
SEC16B SEC16 homolog B (S. cerevisiae) 1q25.2 1(0/1/0) IMP
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2p25 1(0/1/0) ISS
NGF nerve growth factor (beta polypeptide) 1p13.1 2(2/0/0) IMP[16153003]
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 17q11.2 26(13/13/0) IEA

Genes from other sources Help (count: 19)

Approved Symbol Approved Name Source Evidence[PMID]
IL18 interleukin 18 (interferon-gamma-inducing factor) Mapped by significant region IEA
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 Mapped by significant region ISS
WNT10A wingless-type MMTV integration site family, member 10A Mapped by significant region IEA
MED1 mediator complex subunit 1 Mapped by LD-proxy; Mapped by PBA pathway IDA[17827210]; IMP[17223341]
FLCN folliculin Mapped by significant region ISS
FGF9 fibroblast growth factor 9 Mapped by significant region IEA
MUSK muscle, skeletal, receptor tyrosine kinase Mapped by significant region ISS
RBM4B RNA binding motif protein 4B Mapped by significant region IEA
PRDM1 PR domain containing 1, with ZNF domain Mapped by CNV IEA
WNT11 wingless-type MMTV integration site family, member 11 Mapped by significant region IMP
LRRC32 leucine rich repeat containing 32 Mapped by significant region IEA
HINFP histone H4 transcription factor Mapped by significant region IMP[14585971]
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit Mapped by significant region IDA[17028174]
IL7R interleukin 7 receptor Mapped by significant region IEA
CTGF connective tissue growth factor Mapped by significant region IEA
TMED2 transmembrane emp24 domain trafficking protein 2 Mapped by CNV IEA
TNC tenascin C Mapped by significant region IEA
MAPK9 mitogen-activated protein kinase 9 Mapped by CNV IMP[18262097]
WNT6 wingless-type MMTV integration site family, member 6 Mapped by significant region IMP