ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0016055
Name	Wnt receptor signaling pathway
Type	biological process
No. of Genes in ADHDgene	25
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 25)

Literature-origin genes (count: 4)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
DRD2	dopamine receptor D2	11q22-q23	10(3/7/0)	IEA
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	9q21.32	1(1/0/0)	IEA
TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	9q21.32	1(1/0/0)	IEA
DACT1	dishevelled-binding antagonist of beta-catenin 1	14q22.3	1(0/1/0)	IEA

Genes from other sources (count: 21)

Approved Symbol	Approved Name	Source	Evidence[PMID]
MARK2	MAP/microtubule affinity-regulating kinase 2	Mapped by significant region	IEA
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	Mapped by significant region	TAS[18784435]
CTNND1	catenin (cadherin-associated protein), delta 1	Mapped by significant region	IEA
WWOX	WW domain containing oxidoreductase	Mapped by significant region	IEA
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2	Mapped by CNV	ISS
NKD2	naked cuticle homolog 2 (Drosophila)	Mapped by significant region	IEA
DDB1	damage-specific DNA binding protein 1, 127kDa	Mapped by significant region	IEA
HBP1	HMG-box transcription factor 1	Mapped by CNV	IEA
PYGO1	pygopus family PHD finger 1	Mapped by Literature SNP	IEA
AMOTL1	angiomotin like 1	Mapped by significant region	IEA
DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	Mapped by significant region	IEA
INVS	inversin	Mapped by significant region	IEA
FZD4	frizzled class receptor 4	Mapped by significant region	IDA[17955262]
KREMEN2	kringle containing transmembrane protein 2	Mapped by significant region	IEA
LRP5	low density lipoprotein receptor-related protein 5	Mapped by CNV; Mapped by significant region	IDA[17955262]
RNF146	ring finger protein 146	Mapped by significant region	IEA
RNF138	ring finger protein 138, E3 ubiquitin protein ligase	Mapped by significant region	IEA
USP34	ubiquitin specific peptidase 34	Mapped by LD-proxy	IEA
AMER3	APC membrane recruitment protein 3	Mapped by CNV; Mapped by significant region	IEA
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	Mapped by significant region	IEA
TGFB1I1	transforming growth factor beta 1 induced transcript 1	Mapped by PBA pathway	IEA