ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0016055
Name Wnt receptor signaling pathway
Type biological process
No. of Genes in ADHDgene  25
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 25)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0) IEA
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 9q21.32 1(1/0/0) IEA
TLE4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 9q21.32 1(1/0/0) IEA
DACT1 dishevelled-binding antagonist of beta-catenin 1 14q22.3 1(0/1/0) IEA

Genes from other sources Help (count: 21)

Approved Symbol Approved Name Source Evidence[PMID]
MARK2 MAP/microtubule affinity-regulating kinase 2 Mapped by significant region IEA
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) Mapped by significant region TAS[18784435]
CTNND1 catenin (cadherin-associated protein), delta 1 Mapped by significant region IEA
WWOX WW domain containing oxidoreductase Mapped by significant region IEA
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 Mapped by CNV ISS
NKD2 naked cuticle homolog 2 (Drosophila) Mapped by significant region IEA
DDB1 damage-specific DNA binding protein 1, 127kDa Mapped by significant region IEA
HBP1 HMG-box transcription factor 1 Mapped by CNV IEA
PYGO1 pygopus family PHD finger 1 Mapped by Literature SNP IEA
AMOTL1 angiomotin like 1 Mapped by significant region IEA
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) Mapped by significant region IEA
INVS inversin Mapped by significant region IEA
FZD4 frizzled class receptor 4 Mapped by significant region IDA[17955262]
KREMEN2 kringle containing transmembrane protein 2 Mapped by significant region IEA
LRP5 low density lipoprotein receptor-related protein 5 Mapped by CNV; Mapped by significant region IDA[17955262]
RNF146 ring finger protein 146 Mapped by significant region IEA
RNF138 ring finger protein 138, E3 ubiquitin protein ligase Mapped by significant region IEA
USP34 ubiquitin specific peptidase 34 Mapped by LD-proxy IEA
AMER3 APC membrane recruitment protein 3 Mapped by CNV; Mapped by significant region IEA
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit Mapped by significant region IEA
TGFB1I1 transforming growth factor beta 1 induced transcript 1 Mapped by PBA pathway IEA