ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0003674
Name molecular_function
Type molecular function
No. of Genes in ADHDgene  149
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 149)

Literature-origin genes (count: 5)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TMEM132B transmembrane protein 132B 12q24.31 1(0/1/0) ND
REEP5 receptor accessory protein 5 5q22-q23 1(0/0/1) ND
DMRT2 doublesex and mab-3 related transcription factor 2 9p24.3 1(0/0/1) ND
TLE4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 9q21.32 1(1/0/0) ND
ZNF75A zinc finger protein 75a 16p13.11 1(0/0/1) ND

Genes from other sources Help (count: 144)

Approved Symbol Approved Name Source Evidence[PMID]
NAAA N-acylethanolamine acid amidase Mapped by CNV ND
TMEM126B transmembrane protein 126B Mapped by significant region ND
RER1 retention in endoplasmic reticulum sorting receptor 1 Mapped by PBA pathway ND
PRM3 protamine 3 Mapped by significant region ND
TM6SF2 transmembrane 6 superfamily member 2 Mapped by LD-proxy ND
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 Mapped by CNV ND
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 Mapped by significant region ND
LINC00474 long intergenic non-protein coding RNA 474 Mapped by significant region ND
ACSM2B acyl-CoA synthetase medium-chain family member 2B Mapped by significant region ND
SPATA4 spermatogenesis associated 4 Mapped by LD-proxy ND
WDR74 WD repeat domain 74 Mapped by significant region ND
KIAA1324 KIAA1324 Mapped by CNV ND
MAGEL2 MAGE-like 2 Mapped by CNV; Mapped by significant region ND
L3MBTL3 l(3)mbt-like 3 (Drosophila) Mapped by CNV; Mapped by significant region ND
WDR59 WD repeat domain 59 Mapped by significant region ND
CFDP1 craniofacial development protein 1 Mapped by significant region ND
NOP9 NOP9 nucleolar protein Mapped by significant region ND
KHNYN KH and NYN domain containing Mapped by significant region ND
MFRP membrane frizzled-related protein Mapped by significant region ND
ZNF77 zinc finger protein 77 Mapped by CNV ND
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) Mapped by significant region ND
DOPEY2 dopey family member 2 Mapped by PBA pathway ND
TMEM132D transmembrane protein 132D Mapped by CNV ND
RPS12 ribosomal protein S12 Mapped by significant region ND
TARSL2 threonyl-tRNA synthetase-like 2 Mapped by CNV ND
DGCR14 DiGeorge syndrome critical region gene 14 Mapped by CNV ND
APOL4 apolipoprotein L, 4 Mapped by CNV ND
C11orf1 chromosome 11 open reading frame 1 Mapped by significant region ND
CRYBA2 crystallin, beta A2 Mapped by significant region ND
FAM129A family with sequence similarity 129, member A Mapped by significant region ND
ZC3H12C zinc finger CCCH-type containing 12C Mapped by significant region ND
INO80C INO80 complex subunit C Mapped by significant region ND
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 Mapped by CNV ND
FXYD6 FXYD domain containing ion transport regulator 6 Mapped by significant region ND
CDH9 cadherin 9, type 2 (T1-cadherin) Mapped by significant region ND
SART1 squamous cell carcinoma antigen recognized by T cells Mapped by significant region ND
GAN gigaxonin Mapped by significant region ND
AQP11 aquaporin 11 Mapped by significant region ND
C2CD2L C2CD2-like Mapped by significant region ND
NLRC3 NLR family, CARD domain containing 3 Mapped by significant region ND
IMPACT impact RWD domain protein Mapped by significant region ND
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) Mapped by significant region ND
CLPB ClpB caseinolytic peptidase B homolog (E. coli) Mapped by significant region ND
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 Mapped by significant region ND
CDIP1 cell death-inducing p53 target 1 Mapped by significant region ND
NXPH4 neurexophilin 4 Mapped by CNV ND
ACOXL acyl-CoA oxidase-like Mapped by LD-proxy ND
GCOM2 GRINL1B complex locus 2, pseudogene Mapped by significant region ND
TMEM109 transmembrane protein 109 Mapped by significant region ND
GAS8 growth arrest-specific 8 Mapped by significant region ND
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1 Mapped by Literature SNP ND
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed Mapped by significant region ND
BTNL3 butyrophilin-like 3 Mapped by CNV ND
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 Mapped by significant region ND
TRIM6 tripartite motif containing 6 Mapped by CNV ND
BRIX1 BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) Mapped by significant region ND
TMEM8A transmembrane protein 8A Mapped by significant region ND
FRRS1L ferric-chelate reductase 1-like Mapped by significant region ND
AUTS2 autism susceptibility candidate 2 Mapped by CNV ND
C1QTNF3 C1q and tumor necrosis factor related protein 3 Mapped by significant region ND
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 Mapped by CNV ND
RPUSD1 RNA pseudouridylate synthase domain containing 1 Mapped by significant region ND
MYBPHL myosin binding protein H-like Mapped by CNV ND
C5orf45 chromosome 5 open reading frame 45 Mapped by CNV ND
TMEM127 transmembrane protein 127 Mapped by LD-proxy ND
NOMO1 NODAL modulator 1 Mapped by significant region ND
LPIN1 lipin 1 Mapped by significant region ND
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) Mapped by LD-proxy ND
CDR2 cerebellar degeneration-related protein 2, 62kDa Mapped by CNV; Mapped by significant region ND
NTN3 netrin 3 Mapped by significant region ND
DGCR6 DiGeorge syndrome critical region gene 6 Mapped by CNV ND
ZNF664 zinc finger protein 664 Mapped by CNV ND
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) Mapped by significant region ND
TRIM34 tripartite motif containing 34 Mapped by CNV ND
EPHA6 EPH receptor A6 Mapped by CNV ND
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 Mapped by significant region ND
SLC35F2 solute carrier family 35, member F2 Mapped by significant region ND
ANKRD45 ankyrin repeat domain 45 Mapped by significant region ND
TMEM126A transmembrane protein 126A Mapped by significant region ND
TRIM14 tripartite motif containing 14 Mapped by significant region ND
MPV17L MPV17 mitochondrial membrane protein-like Mapped by CNV; Mapped by significant region ND
KDELC2 KDEL (Lys-Asp-Glu-Leu) containing 2 Mapped by CNV; Mapped by significant region ND
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like Mapped by CNV ND
ZNF688 zinc finger protein 688 Mapped by CNV ND
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 Mapped by significant region ND
FAM184A family with sequence similarity 184, member A Mapped by significant region ND
ZNF142 zinc finger protein 142 Mapped by significant region ND
FSD1L fibronectin type III and SPRY domain containing 1-like Mapped by significant region ND
SCGB2A2 secretoglobin, family 2A, member 2 Mapped by significant region ND
ZNF79 zinc finger protein 79 Mapped by significant region ND
WFDC1 WAP four-disulfide core domain 1 Mapped by CNV; Mapped by significant region ND
HSDL2 hydroxysteroid dehydrogenase like 2 Mapped by significant region ND
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1 Mapped by CNV ND
OR2L3 olfactory receptor, family 2, subfamily L, member 3 Mapped by CNV ND
FLYWCH2 FLYWCH family member 2 Mapped by significant region ND
FITM1 fat storage-inducing transmembrane protein 1 Mapped by significant region ND
MRPL40 mitochondrial ribosomal protein L40 Mapped by CNV ND
NYNRIN NYN domain and retroviral integrase containing Mapped by significant region ND
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) Mapped by significant region ND
C20orf27 chromosome 20 open reading frame 27 Mapped by CNV ND
POLA2 polymerase (DNA directed), alpha 2, accessory subunit Mapped by significant region ND
IFT46 intraflagellar transport 46 homolog (Chlamydomonas) Mapped by significant region ND
TMEM11 transmembrane protein 11 Mapped by significant region ND
KIAA0430 KIAA0430 Mapped by CNV; Mapped by significant region ND
OR2L5 olfactory receptor, family 2, subfamily L, member 5 Mapped by CNV ND
XRRA1 X-ray radiation resistance associated 1 Mapped by significant region ND
ZNF200 zinc finger protein 200 Mapped by significant region ND
CD248 CD248 molecule, endosialin Mapped by significant region ND
EHBP1L1 EH domain binding protein 1-like 1 Mapped by significant region ND
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) Mapped by significant region ND
ORAOV1 oral cancer overexpressed 1 Mapped by significant region ND
TSPYL1 TSPY-like 1 Mapped by significant region ND
NPAP1 nuclear pore associated protein 1 Mapped by CNV; Mapped by significant region ND
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 Mapped by CNV; Mapped by significant region ND
JPH3 junctophilin 3 Mapped by significant region ND
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) Mapped by significant region ND
OR2L2 olfactory receptor, family 2, subfamily L, member 2 Mapped by CNV ND
FADS3 fatty acid desaturase 3 Mapped by LD-proxy; Mapped by significant region ND
CFC1 cripto, FRL-1, cryptic family 1 Mapped by significant region ND
PHF3 PHD finger protein 3 Mapped by significant region ND
CENPV centromere protein V Mapped by significant region ND
DHRS7B dehydrogenase/reductase (SDR family) member 7B Mapped by significant region ND
TTC27 tetratricopeptide repeat domain 27 Mapped by CNV ND
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3 Mapped by significant region ND
CCDC22 coiled-coil domain containing 22 Mapped by LD-proxy ND
TNN tenascin N Mapped by significant region ND
OR2L8 olfactory receptor, family 2, subfamily L, member 8 (gene/pseudogene) Mapped by CNV ND
SCFD2 sec1 family domain containing 2 Mapped by CNV ND
TMX2 thioredoxin-related transmembrane protein 2 Mapped by significant region ND
NPIPB3 nuclear pore complex interacting protein family, member B3 Mapped by significant region ND
COG5 component of oligomeric golgi complex 5 Mapped by CNV ND
C16orf3 chromosome 16 open reading frame 3 Mapped by significant region ND
ATXN2L ataxin 2-like Mapped by LD-proxy ND
SNURF SNRPN upstream reading frame Mapped by CNV; Mapped by significant region ND
ACSM3 acyl-CoA synthetase medium-chain family member 3 Mapped by significant region ND
ABHD3 abhydrolase domain containing 3 Mapped by significant region ND
MFAP4 microfibrillar-associated protein 4 Mapped by significant region ND
ZBTB26 zinc finger and BTB domain containing 26 Mapped by significant region ND
TMEM132A transmembrane protein 132A Mapped by significant region ND
SPEF1 sperm flagellar 1 Mapped by CNV ND
TMEM245 transmembrane protein 245 Mapped by significant region ND
KIAA0368 KIAA0368 Mapped by significant region ND
SMCO4 single-pass membrane protein with coiled-coil domains 4 Mapped by significant region ND
POM121L4P POM121 transmembrane nucleoporin-like 4 pseudogene Mapped by CNV ND