ADHDgene Database

Gene Report

Basic Info

Approved Symbol	ACSM2B
Previous Symbol	ACSM2
Symbol Alias	HXMA, HYST1046
Approved Name	acyl-CoA synthetase medium-chain family member 2B
Previous Name	acyl-CoA synthetase medium-chain family member 2
Name Alias	xenobiotic/medium chain fatty acid:CoA ligase
Location	16p12.3
Position	chr16:20547583-20587695, -
External Links	HGNC: 30931 Entrez Gene: 348158 Ensembl: ENSG00000066813 UCSC: uc002dhk.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16p12.3-12.2	chr16:16800000-24200000	1 (1/0/0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006805	xenobiotic metabolic process	Biological Process		25
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0005759	mitochondrial matrix	Cellular Component		32
GO:0006631	fatty acid metabolic process	Biological Process		15
GO:0046872	metal ion binding	Molecular Function		170
GO:0047760	butyrate-CoA ligase activity	Molecular Function		6
GO:0005524	ATP binding	Molecular Function		228
GO:0005739	mitochondrion	Cellular Component	NAS[19634011]	183
GO:0003674	molecular_function	Molecular Function		126

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00650	Butanoate metabolism	9
hsa01100	Metabolic pathways	237

Genes shared at least 5 GO terms with ACSM2B (count: 5)

Gene Symbol	Pathway Count	Pathway List
ACSM1	6	xenobiotic metabolic process; small molecule metabolic process; mitochondrial matrix; metal ion binding; butyrate-CoA ligase activity; ATP binding;
ACSM2A	6	mitochondrial matrix; fatty acid metabolic process; metal ion binding; butyrate-CoA ligase activity; ATP binding; mitochondrion;
PC	5	small molecule metabolic process; mitochondrial matrix; metal ion binding; ATP binding; mitochondrion;
ACSM3	5	mitochondrial matrix; metal ion binding; butyrate-CoA ligase activity; ATP binding; molecular_function;
ACSM5	5	mitochondrial matrix; fatty acid metabolic process; metal ion binding; butyrate-CoA ligase activity; ATP binding;

Genes shared at least 2 KEGG pathways with ACSM2B (count: 6)

Gene Symbol	Pathway Count	Pathway List
ACAT1	2	Butanoate metabolism; Metabolic pathways;
ACSM1	2	Butanoate metabolism; Metabolic pathways;
ACSM2A	2	Butanoate metabolism; Metabolic pathways;
ACSM3	2	Butanoate metabolism; Metabolic pathways;
ACSM5	2	Butanoate metabolism; Metabolic pathways;
ECHS1	2	Butanoate metabolism; Metabolic pathways;

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Region: chr16:20547583..20587695 View in gBrowse