ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	HOXA3
Previous Symbol	HOX1E, HOX1
Approved Name	homeobox A3
Previous Name	homeo box A3
Location	7p15.2
Position	chr7:27145809-27192200, -
External Links	HGNC: 5104 Entrez Gene: 3200 Ensembl: ENSG00000105997 UCSC: uc011jzk.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
7p15	chr7:20900000-28800000	2 (1/1/0)

Gene related GO terms (count: 18)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0048645	organ formation	Biological Process		2
GO:0048704	embryonic skeletal system morphogenesis	Biological Process		9
GO:0051216	cartilage development	Biological Process		11
GO:0060017	parathyroid gland development	Biological Process		4
GO:0021615	glossopharyngeal nerve morphogenesis	Biological Process		2
GO:0030878	thyroid gland development	Biological Process		7
GO:0043565	sequence-specific DNA binding	Molecular Function		72
GO:0048538	thymus development	Biological Process		14
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0008284	positive regulation of cell proliferation	Biological Process		69
GO:0009952	anterior/posterior pattern specification	Biological Process		26
GO:0010159	specification of organ position	Biological Process		1
GO:0001974	blood vessel remodeling	Biological Process		7
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function		132
GO:0005634	nucleus	Cellular Component		770
GO:0005730	nucleolus	Cellular Component		243
GO:0001525	angiogenesis	Biological Process	IEP[17972163]	35
GO:0071837	HMG box domain binding	Molecular Function		2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with HOXA3 (count: 23)

Gene Symbol	Pathway Count	Pathway List
TBX1	11	parathyroid gland development; thyroid gland development; sequence-specific DNA binding; thymus development; transcription, DNA-dependent; positive regulation of cell proliferation; anterior/posterior pattern specification; blood vessel remodeling; sequence-specific DNA binding transcription factor activity; nucleus; angiogenesis;
HOXB3	9	embryonic skeletal system morphogenesis; cartilage development; glossopharyngeal nerve morphogenesis; thyroid gland development; transcription, DNA-dependent; anterior/posterior pattern specification; sequence-specific DNA binding transcription factor activity; nucleus; angiogenesis;
HOXA5	7	embryonic skeletal system morphogenesis; thyroid gland development; sequence-specific DNA binding; transcription, DNA-dependent; anterior/posterior pattern specification; sequence-specific DNA binding transcription factor activity; nucleus;
HOXA7	7	embryonic skeletal system morphogenesis; sequence-specific DNA binding; transcription, DNA-dependent; anterior/posterior pattern specification; sequence-specific DNA binding transcription factor activity; nucleus; angiogenesis;
HOXB1	7	embryonic skeletal system morphogenesis; sequence-specific DNA binding; transcription, DNA-dependent; anterior/posterior pattern specification; sequence-specific DNA binding transcription factor activity; nucleus; nucleolus;
HOXA4	6	embryonic skeletal system morphogenesis; sequence-specific DNA binding; transcription, DNA-dependent; anterior/posterior pattern specification; sequence-specific DNA binding transcription factor activity; nucleus;
HOXA6	6	embryonic skeletal system morphogenesis; sequence-specific DNA binding; transcription, DNA-dependent; anterior/posterior pattern specification; sequence-specific DNA binding transcription factor activity; nucleus;
HOXA2	6	sequence-specific DNA binding; transcription, DNA-dependent; anterior/posterior pattern specification; sequence-specific DNA binding transcription factor activity; nucleus; nucleolus;
MEN1	5	embryonic skeletal system morphogenesis; sequence-specific DNA binding; transcription, DNA-dependent; nucleus; nucleolus;
FOXD4	5	cartilage development; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; nucleolus;
TGFBR1	5	parathyroid gland development; thymus development; positive regulation of cell proliferation; anterior/posterior pattern specification; angiogenesis;
FGF10	5	thyroid gland development; thymus development; blood vessel remodeling; nucleus; angiogenesis;
FOXE1	5	thyroid gland development; sequence-specific DNA binding; thymus development; sequence-specific DNA binding transcription factor activity; nucleus;
ETS1	5	sequence-specific DNA binding; transcription, DNA-dependent; positive regulation of cell proliferation; sequence-specific DNA binding transcription factor activity; nucleus;
HES1	5	sequence-specific DNA binding; thymus development; positive regulation of cell proliferation; sequence-specific DNA binding transcription factor activity; nucleus;
HNF1B	5	sequence-specific DNA binding; anterior/posterior pattern specification; sequence-specific DNA binding transcription factor activity; nucleus; nucleolus;
HOXA1	5	sequence-specific DNA binding; transcription, DNA-dependent; anterior/posterior pattern specification; sequence-specific DNA binding transcription factor activity; nucleus;
HOXA11	5	sequence-specific DNA binding; transcription, DNA-dependent; anterior/posterior pattern specification; sequence-specific DNA binding transcription factor activity; nucleolus;
HOXA9	5	sequence-specific DNA binding; transcription, DNA-dependent; anterior/posterior pattern specification; sequence-specific DNA binding transcription factor activity; nucleus;
IKZF1	5	sequence-specific DNA binding; thymus development; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; nucleus;
MTA3	5	sequence-specific DNA binding; positive regulation of cell proliferation; sequence-specific DNA binding transcription factor activity; nucleus; nucleolus;
POU2F3	5	sequence-specific DNA binding; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; nucleus; nucleolus;
ELK3	5	transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; nucleus; nucleolus; angiogenesis;

Genes shared at least 2 KEGG pathways with HOXA3 (count: 0)

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Region: chr7:27145809..27192200 View in gBrowse