ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	HSF2
Approved Name	heat shock transcription factor 2
Location	6q22
Position	chr6:122720691-122754264, +
External Links	HGNC: 5225 Entrez Gene: 3298 Ensembl: ENSG00000025156 UCSC: uc003pyu.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
6q22-23	chr6:114600000-139000000	1 (1/0/0)

Gene related GO terms (count: 11)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA[10561509]	131
GO:0042803	protein homodimerization activity	Molecular Function		113
GO:0007283	spermatogenesis	Biological Process		35
GO:0006950	response to stress	Biological Process		30
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function		132
GO:0003713	transcription coactivator activity	Molecular Function	TAS[1871106]	52
GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	Molecular Function	IDA[10561509]	1
GO:0005737	cytoplasm	Cellular Component		690
GO:0006366	transcription from RNA polymerase II promoter	Biological Process	TAS[1871106]	62
GO:0005634	nucleus	Cellular Component		770
GO:0005730	nucleolus	Cellular Component		243

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with HSF2 (count: 13)

Gene Symbol	Pathway Count	Pathway List
TFAP2A	7	positive regulation of transcription from RNA polymerase II promoter; protein homodimerization activity; transcription coactivator activity; cytoplasm; transcription from RNA polymerase II promoter; nucleus; nucleolus;
AATF	5	positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; nucleolus;
FOXP1	5	positive regulation of transcription from RNA polymerase II promoter; protein homodimerization activity; cytoplasm; nucleus; nucleolus;
HES1	5	positive regulation of transcription from RNA polymerase II promoter; protein homodimerization activity; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus;
HNF1B	5	positive regulation of transcription from RNA polymerase II promoter; protein homodimerization activity; sequence-specific DNA binding transcription factor activity; nucleus; nucleolus;
HOXB1	5	positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; nucleolus;
MAF	5	positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; transcription from RNA polymerase II promoter; nucleus;
MLL	5	positive regulation of transcription from RNA polymerase II promoter; protein homodimerization activity; sequence-specific DNA binding transcription factor activity; transcription from RNA polymerase II promoter; nucleus;
POU2F3	5	positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; nucleolus;
RBPJ	5	positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; cytoplasm; nucleus; nucleolus;
PTTG1	5	spermatogenesis; sequence-specific DNA binding transcription factor activity; cytoplasm; transcription from RNA polymerase II promoter; nucleus;
TAF10	5	sequence-specific DNA binding transcription factor activity; transcription coactivator activity; cytoplasm; transcription from RNA polymerase II promoter; nucleus;
TAF4B	5	sequence-specific DNA binding transcription factor activity; cytoplasm; transcription from RNA polymerase II promoter; nucleus; nucleolus;

Genes shared at least 2 KEGG pathways with HSF2 (count: 0)

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Region: chr6:122720691..122754264 View in gBrowse