ADHDgene Database

Gene Report

Basic Info

Approved Symbol	USP37
Symbol Alias	KIAA1594
Approved Name	ubiquitin specific peptidase 37
Previous Name	ubiquitin specific protease 37
Location	2q35
Position	chr2:219314974-219433084, -
External Links	HGNC: 20063 Entrez Gene: 57695 Ensembl: ENSG00000135913 UCSC: uc010fvs.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
2q35	chr2:215300000-221500000	1 (1/0/0)

Gene related GO terms (count: 12)

ID	Name	Type	No. of Genes in ADHDgene
GO:0000082	G1/S transition of mitotic cell cycle	Biological Process	26
GO:0004221	ubiquitin thiolesterase activity	Molecular Function	12
GO:0004197	cysteine-type endopeptidase activity	Molecular Function	17
GO:0005515	protein binding	Molecular Function	910
GO:0004843	ubiquitin-specific protease activity	Molecular Function	9
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	25
GO:0005634	nucleus	Cellular Component	770
GO:0019901	protein kinase binding	Molecular Function	51
GO:0007067	mitosis	Biological Process	39
GO:0051301	cell division	Biological Process	58
GO:0035871	protein K11-linked deubiquitination	Biological Process	1
GO:0071108	protein K48-linked deubiquitination	Biological Process	3

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with USP37 (count: 9)

Gene Symbol	Pathway Count	Pathway List
USP10	6	ubiquitin thiolesterase activity; cysteine-type endopeptidase activity; protein binding; ubiquitin-specific protease activity; ubiquitin-dependent protein catabolic process; nucleus;
USP34	6	ubiquitin thiolesterase activity; cysteine-type endopeptidase activity; protein binding; ubiquitin-specific protease activity; ubiquitin-dependent protein catabolic process; protein K48-linked deubiquitination;
CCND1	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; protein kinase binding; cell division;
CDCA5	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; mitosis; cell division;
LATS2	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; mitosis; cell division;
RBBP8	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; mitosis; cell division;
RCC1	5	G1/S transition of mitotic cell cycle; protein binding; nucleus; mitosis; cell division;
USP2	5	ubiquitin thiolesterase activity; cysteine-type endopeptidase activity; protein binding; ubiquitin-dependent protein catabolic process; nucleus;
USP28	5	ubiquitin thiolesterase activity; protein binding; ubiquitin-specific protease activity; ubiquitin-dependent protein catabolic process; nucleus;

Genes shared at least 2 KEGG pathways with USP37 (count: 0)

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Region: chr2:219314974..219433084 View in gBrowse