ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SS18
Previous Symbol	SSXT
Symbol Alias	SYT
Approved Name	synovial sarcoma translocation, chromosome 18
Location	18q11.2
Position	chr18:23596217-23670611, -
External Links	HGNC: 11340 Entrez Gene: 6760 Ensembl: ENSG00000141380 UCSC: uc002kvm.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q11.2-12.3	chr18:19000000-43500000	1 (1/0/0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000226	microtubule cytoskeleton organization	Biological Process		39

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0048013	ephrin receptor signaling pathway	Biological Process		2
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA[15919756]	131
GO:0042493	response to drug	Biological Process		68
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	Molecular Function	IDA[15919756]	19
GO:0007243	intracellular protein kinase cascade	Biological Process		19
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0005881	cytoplasmic microtubule	Cellular Component		8
GO:0005634	nucleus	Cellular Component		770
GO:0005515	protein binding	Molecular Function		910
GO:0000902	cell morphogenesis	Biological Process		7

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SS18 (count: 4)

Gene Symbol	Pathway Count	Pathway List
KDM1A	5	positive regulation of transcription from RNA polymerase II promoter; ligand-dependent nuclear receptor transcription coactivator activity; transcription, DNA-dependent; nucleus; protein binding;
MED1	5	positive regulation of transcription from RNA polymerase II promoter; ligand-dependent nuclear receptor transcription coactivator activity; nucleus; protein binding; cell morphogenesis;
NCOA7	5	positive regulation of transcription from RNA polymerase II promoter; ligand-dependent nuclear receptor transcription coactivator activity; transcription, DNA-dependent; nucleus; protein binding;
SREBF1	5	positive regulation of transcription from RNA polymerase II promoter; response to drug; transcription, DNA-dependent; nucleus; protein binding;

Genes shared at least 2 KEGG pathways with SS18 (count: 0)

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Region: chr18:23596217..23670611 View in gBrowse