ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PAFAH1B2
Approved Name	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
Previous Name	platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa, "platelet-activating factor acetylhydrolase, isoform Ib, subunit 2 (30kDa)"
Name Alias	PAF-AH1b alpha 2 subunit
Location	11q23
Position	chr11:117014983-117047610, +
External Links	HGNC: 8575 Entrez Gene: 5049 Ensembl: ENSG00000168092 UCSC: uc001pqe.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005730	nucleolus	Cellular Component		243
GO:0005737	cytoplasm	Cellular Component	TAS[16130169]	690
GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity	Molecular Function		1
GO:0046982	protein heterodimerization activity	Molecular Function		68
GO:0042803	protein homodimerization activity	Molecular Function		113
GO:0016239	positive regulation of macroautophagy	Biological Process		2
GO:0016042	lipid catabolic process	Biological Process		32
GO:0007420	brain development	Biological Process		33
GO:0007283	spermatogenesis	Biological Process		35
GO:0006629	lipid metabolic process	Biological Process	TAS[9144386]	51
GO:0005886	plasma membrane	Cellular Component		772
GO:0005829	cytosol	Cellular Component		447

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00565	Ether lipid metabolism	15

Genes shared at least 5 GO terms with PAFAH1B2 (count: 2)

Gene Symbol	Pathway Count	Pathway List
PAFAH1B1	5	nucleolus; cytoplasm; protein homodimerization activity; lipid catabolic process; cytosol;
FZD4	5	cytoplasm; protein heterodimerization activity; protein homodimerization activity; brain development; plasma membrane;

Genes shared at least 2 KEGG pathways with PAFAH1B2 (count: 14)

Gene Symbol	Pathway Count	Pathway List
LPCAT1	2	Metabolic pathways; Ether lipid metabolism;
LPCAT4	2	Metabolic pathways; Ether lipid metabolism;
PAFAH1B1	2	Metabolic pathways; Ether lipid metabolism;
PLA2G10	2	Metabolic pathways; Ether lipid metabolism;
PLA2G1B	2	Metabolic pathways; Ether lipid metabolism;
PLA2G2A	2	Metabolic pathways; Ether lipid metabolism;
PLA2G2D	2	Metabolic pathways; Ether lipid metabolism;
PLA2G2E	2	Metabolic pathways; Ether lipid metabolism;
PLA2G3	2	Metabolic pathways; Ether lipid metabolism;
PLA2G4B	2	Metabolic pathways; Ether lipid metabolism;
PLA2G5	2	Metabolic pathways; Ether lipid metabolism;
PLA2G6	2	Metabolic pathways; Ether lipid metabolism;
PLD1	2	Metabolic pathways; Ether lipid metabolism;
PLD2	2	Metabolic pathways; Ether lipid metabolism;

View in gBrowse

Region: chr11:117014983..117047610 View in gBrowse