ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SPATA13
Symbol Alias	FLJ31208, ARHGEF29
Approved Name	spermatogenesis associated 13
Location	13q12.13
Position	chr13:24734861-24896096, +
External Links	HGNC: 23222 Entrez Gene: 221178 Ensembl: ENSG00000182957 UCSC: uc001upd.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_160	chr13:23569913-23657688 (NCBI Build 35 (hg17))	87776	13q12.12	Duplication	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005543	phospholipid binding	Molecular Function		61
GO:0005634	nucleus	Cellular Component		770
GO:0005085	guanyl-nucleotide exchange factor activity	Molecular Function	IDA[19934221]; IMP[17599059]	17
GO:0005515	protein binding	Molecular Function	IPI[17145773]	910
GO:0016477	cell migration	Biological Process	IMP[19151759]	24
GO:0030027	lamellipodium	Cellular Component	IDA[19151759]	27
GO:0005730	nucleolus	Cellular Component		243
GO:0005737	cytoplasm	Cellular Component		690
GO:0030334	regulation of cell migration	Biological Process	IMP[17599059]	10
GO:0030676	Rac guanyl-nucleotide exchange factor activity	Molecular Function	IDA[19934221]; IMP[17599059]	3
GO:0030032	lamellipodium assembly	Biological Process	IMP[17599059]	8
GO:0030175	filopodium	Cellular Component	IDA[17599059]	5
GO:0046847	filopodium assembly	Biological Process	IMP[17599059]	5
GO:0035023	regulation of Rho protein signal transduction	Biological Process		9
GO:0032587	ruffle membrane	Cellular Component	IDA[19151759]	12

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SPATA13 (count: 11)

Gene Symbol	Pathway Count	Pathway List
ARHGEF4	8	phospholipid binding; guanyl-nucleotide exchange factor activity; protein binding; Rac guanyl-nucleotide exchange factor activity; lamellipodium assembly; filopodium assembly; regulation of Rho protein signal transduction; ruffle membrane;
APC	6	nucleus; protein binding; cell migration; lamellipodium; cytoplasm; ruffle membrane;
BAIAP2	6	nucleus; protein binding; nucleolus; cytoplasm; filopodium; filopodium assembly;
NF2	6	nucleus; protein binding; lamellipodium; nucleolus; cytoplasm; ruffle membrane;
ARHGEF2	5	phospholipid binding; protein binding; Rac guanyl-nucleotide exchange factor activity; regulation of Rho protein signal transduction; ruffle membrane;
FGD3	5	phospholipid binding; guanyl-nucleotide exchange factor activity; lamellipodium; cytoplasm; filopodium assembly;
OSBPL1A	5	phospholipid binding; nucleus; protein binding; nucleolus; cytoplasm;
STAP1	5	phospholipid binding; nucleus; protein binding; nucleolus; cytoplasm;
TIAM2	5	phospholipid binding; guanyl-nucleotide exchange factor activity; lamellipodium; filopodium; regulation of Rho protein signal transduction;
GSK3B	5	nucleus; protein binding; cell migration; nucleolus; cytoplasm;
NCK1	5	nucleus; protein binding; cell migration; cytoplasm; lamellipodium assembly;

Genes shared at least 2 KEGG pathways with SPATA13 (count: 0)

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Region: chr13:24734861..24896096 View in gBrowse