ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SPATA13
Symbol Alias	FLJ31208, ARHGEF29
Approved Name	spermatogenesis associated 13
Location	13q12.13
Position	chr13:24553944-24881212, 1
External Links	HGNC: 23222 Entrez Gene: 221178 Ensembl: ENSG00000182957 UCSC: uc021rhg.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by Literature SNP; Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 9)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs17079773	chr13:24598384(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant	1(0/0/1)

rs_ID	Location	Functional Annotation
rs7330947	chr13:24607400(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant
rs17079801	chr13:24608624(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant
rs12430935	chr13:24600633(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant
rs10507336	chr13:24605800(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant
rs17079755	chr13:24592790(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant
rs17079770	chr13:24594667(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant
rs9510997	chr13:24592857(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant
rs4770552	chr13:24594430(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_160	chr13:23569913-23657688 (NCBI Build 35 (hg17))	87776	13q12.12	Duplication	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0035023	regulation of Rho protein signal transduction	biological process	IEA	10
GO:0032587	ruffle membrane	cellular component	IDA[19151759]	12
GO:0030175	filopodium	cellular component	IDA[17599059]	6
GO:0030032	lamellipodium assembly	biological process	IMP[17599059]	9
GO:0030676	Rac guanyl-nucleotide exchange factor activity	molecular function	IDA[19934221]; IMP[17599059]	3
GO:0005085	guanyl-nucleotide exchange factor activity	molecular function	IDA[19934221]; IMP[17599059]	17
GO:0005543	phospholipid binding	molecular function	IEA	66
GO:0005737	cytoplasm	cellular component	IDA	781
GO:0005730	nucleolus	cellular component	IDA	271
GO:0005515	protein binding	molecular function	IPI[17145773]	1015
GO:0030027	lamellipodium	cellular component	IDA[19151759]	29
GO:0005634	nucleus	cellular component	IDA	877
GO:0030334	regulation of cell migration	biological process	IMP[17599059]	10
GO:0046847	filopodium assembly	biological process	IMP[17599059]	5
GO:0016477	cell migration	biological process	IMP[19151759]	25

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SPATA13 (count: 11)

Gene Symbol	Pathway Count	Pathway List
ARHGEF4	8	regulation of Rho protein signal transduction; ruffle membrane; lamellipodium assembly; Rac guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; phospholipid binding; protein binding; filopodium assembly;
APC	6	ruffle membrane; cytoplasm; protein binding; lamellipodium; nucleus; cell migration;
NF2	6	ruffle membrane; cytoplasm; nucleolus; protein binding; lamellipodium; nucleus;
BAIAP2	6	filopodium; cytoplasm; nucleolus; protein binding; nucleus; filopodium assembly;
TIAM2	5	regulation of Rho protein signal transduction; filopodium; guanyl-nucleotide exchange factor activity; phospholipid binding; lamellipodium;
ARHGEF2	5	regulation of Rho protein signal transduction; ruffle membrane; Rac guanyl-nucleotide exchange factor activity; phospholipid binding; protein binding;
NCK1	5	lamellipodium assembly; cytoplasm; protein binding; nucleus; cell migration;
FGD3	5	guanyl-nucleotide exchange factor activity; phospholipid binding; cytoplasm; lamellipodium; filopodium assembly;
OSBPL1A	5	phospholipid binding; cytoplasm; nucleolus; protein binding; nucleus;
STAP1	5	phospholipid binding; cytoplasm; nucleolus; protein binding; nucleus;
GSK3B	5	cytoplasm; nucleolus; protein binding; nucleus; cell migration;

Genes shared at least 2 KEGG pathways with SPATA13 (count: 0)

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Region: chr13:24553944..24881212 View in gBrowse