ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0000186
Name activation of MAPKK activity
Type biological process
No. of Genes in ADHDgene  9
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 9)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
NGF nerve growth factor (beta polypeptide) 1p13.1 2(2/0/0) TAS
GRM1 glutamate receptor, metabotropic 1 6q24 1(1/0/0) IEA

Genes from other sources Help (count: 7)

Approved Symbol Approved Name Source Evidence[PMID]
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy TAS
GADD45G growth arrest and DNA-damage-inducible, gamma Mapped by significant region IEA
TGFBR1 transforming growth factor, beta receptor 1 Mapped by significant region IDA[18625725]
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV TAS
MAP3K5 mitogen-activated protein kinase kinase kinase 5 Mapped by LD-proxy; Mapped by significant region IDA[11959862]
KIDINS220 kinase D-interacting substrate, 220kDa Mapped by significant region TAS
TAOK2 TAO kinase 2 Mapped by CNV IDA[10660600]