ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0030168
Name platelet activation
Type biological process
No. of Genes in ADHDgene  38
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 38)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0) TAS
ADRA2A adrenoceptor alpha 2A 10q25.2 13(4/9/0) TAS
DGKH diacylglycerol kinase, eta 13q13.3 2(1/1/0) TAS
ARRB2 arrestin, beta 2 17p13 1(1/0/0) TAS
ARRB1 arrestin, beta 1 11q13 2(1/1/0) TAS
ADRA2B adrenoceptor alpha 2B 2q11.1 1(1/0/0) TAS
ADRA2C adrenoceptor alpha 2C 4p16.3 7(2/4/1) TAS

Genes from other sources Help (count: 31)

Approved Symbol Approved Name Source Evidence[PMID]
TRPC6 transient receptor potential cation channel, subfamily C, member 6 Mapped by significant region TAS
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Mapped by significant region TAS
DAGLA diacylglycerol lipase, alpha Mapped by significant region TAS
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma Mapped by CNV TAS
STXBP3 syntaxin binding protein 3 Mapped by CNV TAS
CFL1 cofilin 1 (non-muscle) Mapped by significant region TAS
BCAR1 breast cancer anti-estrogen resistance 1 Mapped by significant region TAS
PDPK1 3-phosphoinositide dependent protein kinase-1 Mapped by significant region TAS
GP1BB glycoprotein Ib (platelet), beta polypeptide Mapped by CNV NAS[12871509]; TAS
SYK spleen tyrosine kinase Mapped by significant region TAS
FN1 fibronectin 1 Mapped by significant region TAS
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 Mapped by significant region TAS
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) Mapped by significant region TAS
TUBA4A tubulin, alpha 4a Mapped by significant region TAS
POTEKP POTE ankyrin domain family, member K, pseudogene Mapped by significant region TAS
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy TAS
VEGFB vascular endothelial growth factor B Mapped by significant region TAS
HABP4 hyaluronan binding protein 4 Mapped by significant region TAS
F2RL2 coagulation factor II (thrombin) receptor-like 2 Mapped by PBA pathway TAS
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Mapped by significant region TAS
IL6 interleukin 6 (interferon, beta 2) Mapped by significant region TAS[7831669]
ALDOA aldolase A, fructose-bisphosphate Mapped by CNV TAS
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 Mapped by CNV TAS
TRPC3 transient receptor potential cation channel, subfamily C, member 3 Mapped by PBA pathway TAS
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV TAS
APOA1 apolipoprotein A-I Mapped by significant region TAS
MGLL monoglyceride lipase Mapped by PBA pathway TAS
DGKG diacylglycerol kinase, gamma 90kDa Mapped by Literature SNP TAS
STX4 syntaxin 4 Mapped by CNV TAS
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 Mapped by Literature SNP TAS
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) Mapped by significant region TAS