ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa04350
Name TGF-beta signaling pathway
No. of Genes in ADHDgene  11
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 11)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
BMPR1B bone morphogenetic protein receptor, type IB 4q23-q24 1(0/0/1)
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 4p16.1 1(1/0/0)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2p25 1(0/1/0)

Genes from other sources Help(count: 8)

Approved Symbol Approved Name Location Source
MAPK3 mitogen-activated protein kinase 3 16p11.2 Mapped by CNV
TGFBR1 transforming growth factor, beta receptor 1 9q22 Mapped by significant region
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 11q23.1 Mapped by significant region
CREBBP CREB binding protein 16p13.3 Mapped by significant region
MAPK1 mitogen-activated protein kinase 1 22q11.2 Mapped by LD-proxy
LTBP1 latent transforming growth factor beta binding protein 1 2p22-p21 Mapped by CNV
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 2p24 Mapped by significant region
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 11q13.1 Mapped by significant region