ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005524
Name ATP binding
Type Molecular Function
No. of Genes in ADHDgene  228
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 228)

Literature-origin genes (count: 26)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 11p11.2 1(0/0/1)
CDK20 cyclin-dependent kinase 20 9q22.1 1(0/1/0)
MAP2K3 mitogen-activated protein kinase kinase 3 17q11.2 1(0/1/0)
TRIO triple functional domain (PTPRF interacting) 5p14-p15.1 1(0/0/1)
ADRBK1 adrenergic, beta, receptor kinase 1 11q13 1(0/1/0)
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 16q24.1 2(0/1/1)
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 Xq28 1(0/1/0)
ATP11A ATPase, class VI, type 11A 13q34 1(0/1/0)
MYO5B myosin VB 18q 1(0/1/0)
ADRBK2 adrenergic, beta, receptor kinase 2 22q11 1(0/1/0)
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0)
DCLK1 doublecortin-like kinase 1 13q13.3 1(1/0/0)
HK1 hexokinase 1 10q22 1(0/1/0)
DCLK2 doublecortin-like kinase 2 4q31.3 1(0/0/1)
BMPR1B bone morphogenetic protein receptor, type IB 4q23-q24 1(0/0/1) IDA[12065756]
CAMK1D calcium/calmodulin-dependent protein kinase ID 10p13 1(0/0/1)
DGKH diacylglycerol kinase, eta 13q13.3 1(1/0/0)
AK8 adenylate kinase 8 9q34.13 1(0/0/1)
NADSYN1 NAD synthetase 1 11q13.4 1(0/0/1)
PRKG1 protein kinase, cGMP-dependent, type I 10q11.2 1(0/0/1)
HKDC1 hexokinase domain containing 1 10q22.1 1(0/1/0)
SYN3 synapsin III 22q12.3 1(0/1/0)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 1(1/0/0)
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 7q35-q36 1(0/0/1) IDA[15877279]
CSNK1E casein kinase 1, epsilon 22q13.1 2(1/1/0)
ATPBD4 ATP binding domain 4 15q14 1(0/0/1)

Genes from other sources Help (count: 202)

Approved Symbol Approved Name Source Evidence[PMID]
FLT4 fms-related tyrosine kinase 4 Mapped by CNV
AACS acetoacetyl-CoA synthetase Mapped by CNV
SRCAP Snf2-related CREBBP activator protein Mapped by CNV
EPHA5 EPH receptor A5 Mapped by CNV; Mapped by significant region
SMC3 structural maintenance of chromosomes 3 Mapped by PBA pathway
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 Mapped by significant region
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific Mapped by significant region
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 Mapped by PBA pathway
MYO7A myosin VIIA Mapped by significant region
FRK fyn-related kinase Mapped by significant region
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region
MARK4 MAP/microtubule affinity-regulating kinase 4 Mapped by PBA pathway NAS[15009667]
DDX25 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 Mapped by significant region
CDK12 cyclin-dependent kinase 12 Mapped by LD-proxy
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 Mapped by LD-proxy; Mapped by significant region
IGHMBP2 immunoglobulin mu binding protein 2 Mapped by CNV; Mapped by significant region IDA[19158098]
SMG1 smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) Mapped by significant region
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 Mapped by CNV
CDK10 cyclin-dependent kinase 10 Mapped by significant region
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 Mapped by CNV
OASL 2'-5'-oligoadenylate synthetase-like Mapped by PBA pathway
MYLK4 myosin light chain kinase family, member 4 Mapped by CNV
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 Mapped by PBA pathway
CHKA choline kinase alpha Mapped by significant region
KIF11 kinesin family member 11 Mapped by PBA pathway
PSKH2 protein serine kinase H2 Mapped by CNV
PHKG2 phosphorylase kinase, gamma 2 (testis) Mapped by CNV
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 Mapped by CNV
MARK2 MAP/microtubule affinity-regulating kinase 2 Mapped by significant region IDA[14976552]
SMC1A structural maintenance of chromosomes 1A Mapped by PBA pathway
DDX6 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 Mapped by significant region
MYH11 myosin, heavy chain 11, smooth muscle Mapped by CNV; Mapped by significant region
AATK apoptosis-associated tyrosine kinase Mapped by LD-proxy
ADCY4 adenylate cyclase 4 Mapped by significant region
KIF12 kinesin family member 12 Mapped by significant region
SEPHS2 selenophosphate synthetase 2 Mapped by CNV
ATP13A4 ATPase type 13A4 Mapped by CNV
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 Mapped by CNV; Mapped by significant region IDA[11700048]
KIF19 kinesin family member 19 Mapped by CNV
ILK integrin-linked kinase Mapped by CNV
NRBP1 nuclear receptor binding protein 1 Mapped by PBA pathway
ROS1 c-ros oncogene 1 , receptor tyrosine kinase Mapped by significant region
SMC2 structural maintenance of chromosomes 2 Mapped by significant region
PI4K2B phosphatidylinositol 4-kinase type 2 beta Mapped by CNV
KIF1C kinesin family member 1C Mapped by PBA pathway
EARS2 glutamyl-tRNA synthetase 2, mitochondrial (putative) Mapped by significant region
EPHA6 EPH receptor A6 Mapped by CNV
ANKK1 ankyrin repeat and kinase domain containing 1 Mapped by LD-proxy; Mapped by literature SNP; Mapped by significant region
MYO19 myosin XIX Mapped by CNV
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha Mapped by CNV
ITK IL2-inducible T-cell kinase Mapped by significant region
ATP10A ATPase, class V, type 10A Mapped by CNV; Mapped by significant region
KIF22 kinesin family member 22 Mapped by CNV
MYO15A myosin XVA Mapped by significant region
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) Mapped by LD-proxy
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 Mapped by significant region NAS[12697999]
UBA6 ubiquitin-like modifier activating enzyme 6 Mapped by significant region
ATAD5 ATPase family, AAA domain containing 5 Mapped by CNV
KIF23 kinesin family member 23 Mapped by PBA pathway
DHX15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 Mapped by CNV; Mapped by PBA pathway
NARS asparaginyl-tRNA synthetase Mapped by significant region
CLP1 CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae) Mapped by significant region TAS[8896421]
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 Mapped by significant region
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 Mapped by CNV TAS[11504732]
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 Mapped by significant region IDA[10837493]
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) Mapped by significant region
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 Mapped by PBA pathway
KIF2C kinesin family member 2C Mapped by PBA pathway
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mapped by CNV; Mapped by significant region
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 Mapped by CNV
RIPK3 receptor-interacting serine-threonine kinase 3 Mapped by significant region
TAOK2 TAO kinase 2 Mapped by CNV
FASTK Fas-activated serine/threonine kinase Mapped by LD-proxy; Mapped by literature SNP
CAMK2D calcium/calmodulin-dependent protein kinase II delta Mapped by CNV
PC pyruvate carboxylase Mapped by significant region
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) Mapped by LD-proxy
PIK3C3 phosphoinositide-3-kinase, class 3 Mapped by significant region
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 Mapped by CNV; Mapped by significant region
DHX9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 Mapped by significant region
RIOK3 RIO kinase 3 (yeast) Mapped by significant region
SARS seryl-tRNA synthetase Mapped by CNV
KIFC1 kinesin family member C1 Mapped by LD-proxy NAS[8276466]
ERN2 endoplasmic reticulum to nucleus signaling 2 Mapped by significant region IDA[11175748]
MAPK9 mitogen-activated protein kinase 9 Mapped by CNV
ULK2 unc-51-like kinase 2 (C. elegans) Mapped by significant region
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 Mapped by LD-proxy
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 Mapped by CNV
CARNS1 carnosine synthase 1 Mapped by significant region
PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide Mapped by CNV
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 Mapped by significant region
POTEE POTE ankyrin domain family, member E Mapped by CNV; Mapped by significant region
YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 Mapped by CNV
POTEF POTE ankyrin domain family, member F Mapped by significant region
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) Mapped by CNV
POTEI POTE ankyrin domain family, member I Mapped by significant region
CLPB ClpB caseinolytic peptidase B homolog (E. coli) Mapped by significant region
HYOU1 hypoxia up-regulated 1 Mapped by significant region
POTEJ POTE ankyrin domain family, member J Mapped by significant region
ACACA acetyl-CoA carboxylase alpha Mapped by CNV
POTEKP POTE ankyrin domain family, member K, pseudogene Mapped by significant region
HSPA12B heat shock 70kD protein 12B Mapped by CNV
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Mapped by significant region
MAPK7 mitogen-activated protein kinase 7 Mapped by significant region
IARS isoleucyl-tRNA synthetase Mapped by significant region
NEK6 NIMA (never in mitosis gene a)-related kinase 6 Mapped by significant region IDA[14563848]
DNAH10 dynein, axonemal, heavy chain 10 Mapped by CNV
P2RX6 purinergic receptor P2X, ligand-gated ion channel, 6 Mapped by CNV NAS[12088286]
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) Mapped by significant region IDA[15194684]; NAS[9341881]
DNAH11 dynein, axonemal, heavy chain 11 Mapped by significant region
TOP3B topoisomerase (DNA) III beta Mapped by LD-proxy; Mapped by literature SNP
PRKD1 protein kinase D1 Mapped by significant region
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit Mapped by PBA pathway
PLK1 polo-like kinase 1 Mapped by significant region
SYK spleen tyrosine kinase Mapped by significant region
TGFBR1 transforming growth factor, beta receptor 1 Mapped by significant region IDA[12065756]
AURKC aurora kinase C Mapped by LD-proxy
TARSL2 threonyl-tRNA synthetase-like 2 Mapped by CNV
EEF2K eukaryotic elongation factor-2 kinase Mapped by CNV; Mapped by significant region
P2RX3 purinergic receptor P2X, ligand-gated ion channel, 3 Mapped by significant region NAS[17895406]
TARS threonyl-tRNA synthetase Mapped by significant region
DARS2 aspartyl-tRNA synthetase 2, mitochondrial Mapped by significant region TAS[15779907]
DNAH3 dynein, axonemal, heavy chain 3 Mapped by significant region
DAK dihydroxyacetone kinase 2 homolog (S. cerevisiae) Mapped by significant region
TOP3A topoisomerase (DNA) III alpha Mapped by significant region
SPEF2 sperm flagellar 2 Mapped by significant region
BCS1L BCS1-like (S. cerevisiae) Mapped by significant region
EHD3 EH-domain containing 3 Mapped by CNV
SGK1 serum/glucocorticoid regulated kinase 1 Mapped by significant region
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 Mapped by significant region IDA[9792677]
SPEG SPEG complex locus Mapped by significant region
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) Mapped by significant region
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) Mapped by significant region
GLUL glutamate-ammonia ligase Mapped by significant region
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) Mapped by significant region
TRPV1 transient receptor potential cation channel, subfamily V, member 1 Mapped by PBA pathway
MTHFSD methenyltetrahydrofolate synthetase domain containing Mapped by significant region
EHD1 EH-domain containing 1 Mapped by significant region
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 Mapped by significant region
CLCN6 chloride channel 6 Mapped by LD-proxy
ACSF3 acyl-CoA synthetase family member 3 Mapped by CNV; Mapped by significant region
ACSM1 acyl-CoA synthetase medium-chain family member 1 Mapped by significant region
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV
PRKCB protein kinase C, beta Mapped by significant region
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase Mapped by significant region
GAK cyclin G associated kinase Mapped by LD-proxy
KCNJ1 potassium inwardly-rectifying channel, subfamily J, member 1 Mapped by significant region
NUBPL nucleotide binding protein-like Mapped by significant region
NMNAT3 nicotinamide nucleotide adenylyltransferase 3 Mapped by CNV
ACSM3 acyl-CoA synthetase medium-chain family member 3 Mapped by significant region
MLKL mixed lineage kinase domain-like Mapped by significant region
ACSM2B acyl-CoA synthetase medium-chain family member 2B Mapped by significant region
FES feline sarcoma oncogene Mapped by LD-proxy
MCM9 minichromosome maintenance complex component 9 Mapped by significant region
WNK2 WNK lysine deficient protein kinase 2 Mapped by significant region
ACSM2A acyl-CoA synthetase medium-chain family member 2A Mapped by significant region
NLRP10 NLR family, pyrin domain containing 10 Mapped by CNV
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 Mapped by significant region
NLRP14 NLR family, pyrin domain containing 14 Mapped by CNV
PNPLA8 patatin-like phospholipase domain containing 8 Mapped by PBA pathway NAS[10744668]
CHD1L chromodomain helicase DNA binding protein 1-like Mapped by CNV
NLRX1 NLR family member X1 Mapped by significant region
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit Mapped by significant region
ACSM5 acyl-CoA synthetase medium-chain family member 5 Mapped by significant region
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 Mapped by significant region
CHEK1 CHK1 checkpoint homolog (S. pombe) Mapped by significant region
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) Mapped by significant region
STK32C serine/threonine kinase 32C Mapped by CNV
CBWD1 COBW domain containing 1 Mapped by CNV
STK36 serine/threonine kinase 36 Mapped by significant region TAS[10806483]
ROR2 receptor tyrosine kinase-like orphan receptor 2 Mapped by significant region
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy
LATS1 LATS, large tumor suppressor, homolog 1 (Drosophila) Mapped by PBA pathway IDA[10518011]
STK31 serine/threonine kinase 31 Mapped by CNV; Mapped by significant region
STK32B serine/threonine kinase 32B Mapped by CNV
PANK2 pantothenate kinase 2 Mapped by CNV
STK16 serine/threonine kinase 16 Mapped by significant region
CKMT1A creatine kinase, mitochondrial 1A Mapped by LD-proxy
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit Mapped by significant region
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 Mapped by significant region IDA[7830796]
TSSK2 testis-specific serine kinase 2 Mapped by CNV
SCYL1 SCY1-like 1 (S. cerevisiae) Mapped by significant region
HSPA8 heat shock 70kDa protein 8 Mapped by significant region
MAP3K11 mitogen-activated protein kinase kinase kinase 11 Mapped by significant region
ALPK2 alpha-kinase 2 Mapped by significant region
FDXACB1 ferredoxin-fold anticodon binding domain containing 1 Mapped by significant region
THRAP3 thyroid hormone receptor associated protein 3 Mapped by PBA pathway
TSSK4 testis-specific serine kinase 4 Mapped by significant region IDA[15964553]
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 Mapped by CNV
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 Mapped by significant region IDA[11784851]
BCKDK branched chain ketoacid dehydrogenase kinase Mapped by CNV
KARS lysyl-tRNA synthetase Mapped by significant region
HSPA6 heat shock 70kDa protein 6 (HSP70B') Mapped by CNV
MUSK muscle, skeletal, receptor tyrosine kinase Mapped by significant region
SIK2 salt-inducible kinase 2 Mapped by significant region IDA[14976552]
HSPA7 heat shock 70kDa protein 7 (HSP70B) Mapped by CNV
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 Mapped by significant region
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) Mapped by significant region IDA[10871863]
MVD mevalonate (diphospho) decarboxylase Mapped by significant region
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 Mapped by significant region
MAP3K5 mitogen-activated protein kinase kinase kinase 5 Mapped by LD-proxy; Mapped by significant region IDA[17210579]
TTK TTK protein kinase Mapped by PBA pathway
SIK3 SIK family kinase 3 Mapped by significant region IDA[14976552]

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014