Gene Report
Basic Info
Approved Symbol |
ABCC6
|
Previous Symbol |
ARA, PXE |
Symbol Alias |
MRP6, EST349056, MLP1, URG7 |
Approved Name |
ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
Previous Name |
pseudoxanthoma elasticum |
Location |
16p13.11 |
Position |
chr16:16243422-16317328, - |
External Links |
HGNC: 57
Entrez Gene: 368
Ensembl: ENSG00000091262
UCSC: uc002den.3
|
No. of Studies |
0 (significant: 0; non-significant: 0; trend: 0) |
Source |
Mapped by CNV; Mapped by significant region |
Gene related studies (count: 0)
Gene related SNPs (count: 0)
Gene related CNVs (count: 9)
Gene related other variant (count: 0)
Gene related regions (count: 1)
Gene related GO terms (count: 11)
Gene related KEGG pathways (count: 1)
ID |
Name |
No. of Genes in ADHDgene |
Brief Description |
hsa02010 |
ABC transporters |
7 |
The ATP-binding cassette (ABC) transporters form one of the ......
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
More...
|
Genes shared at least 5 GO terms with ABCC6 (count: 6)
Genes shared at least 2 KEGG pathways with ABCC6 (count: 0)
View in gBrowse