ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SLC22A12
Symbol Alias	OAT4L, RST, URAT1
Approved Name	solute carrier family 22 (organic anion/urate transporter), member 12
Previous Name	solute carrier family 22 (organic anion/cation transporter), member 12
Location	11q13.1
Position	chr11:64358113-64369820, +
External Links	HGNC: 17989 Entrez Gene: 116085 Ensembl: ENSG00000197891 UCSC: uc001oam.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0031526	brush border membrane	Cellular Component	NAS[12024214]	6
GO:0030165	PDZ domain binding	Molecular Function	IPI[15304510]	13
GO:0046415	urate metabolic process	Biological Process	IMP[19503597]	4
GO:0042493	response to drug	Biological Process	IDA[12024214]	68
GO:0055085	transmembrane transport	Biological Process		82
GO:0015143	urate transmembrane transporter activity	Molecular Function	IDA[12024214]	1
GO:0005886	plasma membrane	Cellular Component	IDA[16775029]	772
GO:0016021	integral to membrane	Cellular Component	IDA[12024214]	845
GO:0015747	urate transport	Biological Process	IDA[12024214]	1
GO:0019725	cellular homeostasis	Biological Process	NAS[15772301]	2
GO:0016324	apical plasma membrane	Cellular Component	IDA[12024214]	51

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SLC22A12 (count: 3)

Gene Symbol	Pathway Count	Pathway List
SLC34A2	5	brush border membrane; transmembrane transport; plasma membrane; integral to membrane; apical plasma membrane;
ABCG2	5	urate metabolic process; response to drug; transmembrane transport; plasma membrane; integral to membrane;
ABCC6	5	response to drug; transmembrane transport; plasma membrane; integral to membrane; apical plasma membrane;

Genes shared at least 2 KEGG pathways with SLC22A12 (count: 0)

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Region: chr11:64358113..64369820 View in gBrowse