ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SLC34A2
Symbol Alias	NAPI-3B
Approved Name	solute carrier family 34 (sodium phosphate), member 2
Location	4p15.2
Position	chr4:25656923-25680370, +
External Links	HGNC: 11020 Entrez Gene: 10568 Ensembl: ENSG00000157765 UCSC: uc003grr.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_18	chr4:23596065-27014659 (NCBI Build 36.1 (hg18))	3365040	4p15.2	Gain

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0055085	transmembrane transport	Biological Process		82
GO:0043627	response to estrogen stimulus	Biological Process	IEP[12893629]	11
GO:0031526	brush border membrane	Cellular Component		6
GO:0031402	sodium ion binding	Molecular Function	IDA[12488042]	1
GO:0042301	phosphate ion binding	Molecular Function	IDA[12488042]	3
GO:0032355	response to estradiol stimulus	Biological Process		18
GO:0016021	integral to membrane	Cellular Component	IDA[10329428]; NAS[10610722]	845
GO:0015321	sodium-dependent phosphate transmembrane transporter activity	Molecular Function	IDA[10329428]	1
GO:0030643	cellular phosphate ion homeostasis	Biological Process	IDA[10610722]	2
GO:0016324	apical plasma membrane	Cellular Component	IDA[15970207]	51
GO:0006811	ion transport	Biological Process		25
GO:0006817	phosphate ion transport	Biological Process	IDA[10329428]	1
GO:0007568	aging	Biological Process		29
GO:0009750	response to fructose stimulus	Biological Process		1
GO:0001701	in utero embryonic development	Biological Process		32
GO:0005436	sodium:phosphate symporter activity	Molecular Function	IDA[12488042]	1
GO:0005886	plasma membrane	Cellular Component		772
GO:0005887	integral to plasma membrane	Cellular Component	NAS[10329428]	220

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04978	Mineral absorption	7	Minerals are one of the five fundamental groups of nutrients...... Minerals are one of the five fundamental groups of nutrients needed to sustain life. Of the minerals, calcium plays innumerable roles in our bodies, serving as a main component of bone as well as an intracellular messenger in muscle contraction/relaxation, neural networks, the immune system, and endocrine/exocrine cells. Iron, copper, and other metals are required for redox reactions (as cofactors) and for oxygen transport and binding (in hemoglobin and myoglobin). Many enzymes require specific metal atoms to complete their catalytic functions. Animal tissues need moderate quantities of some elements (Ca, P, K, Na, Mg, S, and Cl) and trace amounts of others (Mn, Fe, I, Co, Cr, Cu, Zn, and Se). The minerals are absorbed by either passive or active transport systems through the intestinal mucosa, often using specialized transport proteins, such as ferritin for Fe3+ and vitamin D-induced protein for calcium. More...

Genes shared at least 5 GO terms with SLC34A2 (count: 6)

Gene Symbol	Pathway Count	Pathway List
ATP8B1	5	transmembrane transport; brush border membrane; apical plasma membrane; plasma membrane; integral to plasma membrane;
SLC22A12	5	transmembrane transport; brush border membrane; integral to membrane; apical plasma membrane; plasma membrane;
SLC3A2	5	transmembrane transport; integral to membrane; apical plasma membrane; ion transport; plasma membrane;
SLC6A1	5	transmembrane transport; response to estradiol stimulus; integral to membrane; plasma membrane; integral to plasma membrane;
SLC6A3	5	transmembrane transport; integral to membrane; aging; plasma membrane; integral to plasma membrane;
SLC7A5	5	transmembrane transport; integral to membrane; apical plasma membrane; ion transport; plasma membrane;

Genes shared at least 2 KEGG pathways with SLC34A2 (count: 0)

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Region: chr4:25656923..25680370 View in gBrowse