ADHDgene Database

Gene Report

Basic Info

Approved Symbol	DAK
Symbol Alias	DKFZP586B1621, NET45
Approved Name	dihydroxyacetone kinase 2 homolog (S. cerevisiae)
Previous Name	dihydroxyacetone kinase 2 homolog (yeast)
Location	11q12.2
Position	chr11:61100654-61120767, +
External Links	HGNC: 24552 Entrez Gene: 26007 Ensembl: ENSG00000149476 UCSC: uc001nre.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 8)

ID	Name	Type	No. of Genes in ADHDgene
GO:0050354	triokinase activity	Molecular Function	1
GO:0046872	metal ion binding	Molecular Function	170
GO:0004371	glycerone kinase activity	Molecular Function	1
GO:0005524	ATP binding	Molecular Function	228
GO:0034012	FAD-AMP lyase (cyclizing) activity	Molecular Function	1
GO:0045087	innate immune response	Biological Process	54
GO:0005829	cytosol	Cellular Component	447
GO:0006071	glycerol metabolic process	Biological Process	7

Gene related KEGG pathways (count: 3)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00561	Glycerolipid metabolism	15
hsa04622	RIG-I-like receptor signaling pathway	10	Specific families of pattern recognition receptors are respo...... Specific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular viral replication is recognized by a family of cytosolic RNA helicases termed RIG-I-like receptors (RLRs). The RLR proteins include RIG-I, MDA5, and LGP2 and are expressed in both immune and nonimmune cells. Upon recognition of viral nucleic acids, RLRs recruit specific intracellular adaptor proteins to initiate signaling pathways that lead to the synthesis of type I interferon and other inflammatory cytokines, which are important for eliminating viruses. More...

Genes shared at least 5 GO terms with DAK (count: 0)

Genes shared at least 2 KEGG pathways with DAK (count: 13)

Gene Symbol	Pathway Count	Pathway List
ALDH3A2	2	Metabolic pathways; Glycerolipid metabolism;
DGAT2	2	Metabolic pathways; Glycerolipid metabolism;
DGKH	2	Metabolic pathways; Glycerolipid metabolism;
GPAT2	2	Metabolic pathways; Glycerolipid metabolism;
LIPF	2	Metabolic pathways; Glycerolipid metabolism;
LIPG	2	Metabolic pathways; Glycerolipid metabolism;
MBOAT1	2	Metabolic pathways; Glycerolipid metabolism;
MBOAT2	2	Metabolic pathways; Glycerolipid metabolism;
MGLL	2	Metabolic pathways; Glycerolipid metabolism;
PNLIP	2	Metabolic pathways; Glycerolipid metabolism;
PNLIPRP1	2	Metabolic pathways; Glycerolipid metabolism;
PNLIPRP2	2	Metabolic pathways; Glycerolipid metabolism;
PNPLA3	2	Metabolic pathways; Glycerolipid metabolism;

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Region: chr11:61100654..61120767 View in gBrowse