ADHDgene Database

Gene Report

Basic Info

Approved Symbol	AACS
Symbol Alias	FLJ12389, SUR-5, ACSF1
Approved Name	acetoacetyl-CoA synthetase
Name Alias	acyl-CoA synthetase family member 1
Location	12q24.31
Position	chr12:125549925-125627871, +
External Links	HGNC: 21298 Entrez Gene: 65985 Ensembl: ENSG00000081760 UCSC: uc001uhc.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_26	chr12:122465458-124605386 (NCBI36 / hg18)	2139929	12q24.31-12q24.32	dup

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

ID	Name	Type	No. of Genes in ADHDgene
GO:0001889	liver development	Biological Process	14
GO:0005524	ATP binding	Molecular Function	228
GO:0005829	cytosol	Cellular Component	447
GO:0006631	fatty acid metabolic process	Biological Process	15
GO:0007584	response to nutrient	Biological Process	15
GO:0014074	response to purine-containing compound	Biological Process	2
GO:0030729	acetoacetate-CoA ligase activity	Molecular Function	1
GO:0032024	positive regulation of insulin secretion	Biological Process	5
GO:0034201	response to oleic acid	Biological Process	2
GO:0042493	response to drug	Biological Process	68
GO:0042594	response to starvation	Biological Process	6
GO:0045471	response to ethanol	Biological Process	17
GO:0047760	butyrate-CoA ligase activity	Molecular Function	6
GO:0050872	white fat cell differentiation	Biological Process	2
GO:0060612	adipose tissue development	Biological Process	7
GO:0071394	cellular response to testosterone stimulus	Biological Process	1
GO:0071333	cellular response to glucose stimulus	Biological Process	8
GO:0071397	cellular response to cholesterol	Biological Process	2

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00650	Butanoate metabolism	9

Genes shared at least 5 GO terms with AACS (count: 2)

Gene Symbol	Pathway Count	Pathway List
OXCT1	7	response to nutrient; positive regulation of insulin secretion; response to drug; response to starvation; response to ethanol; adipose tissue development; cellular response to glucose stimulus;
BAD	5	cytosol; positive regulation of insulin secretion; response to oleic acid; response to drug; response to ethanol;

Genes shared at least 2 KEGG pathways with AACS (count: 0)

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Region: chr12:125549925..125627871 View in gBrowse