ADHDgene Database

Gene Report

Basic Info

Approved Symbol	OXCT1
Previous Symbol	OXCT
Symbol Alias	SCOT
Approved Name	3-oxoacid CoA transferase 1
Previous Name	3-oxoacid CoA transferase
Location	5p13
Position	chr5:41730167-41870791, -
External Links	HGNC: 8527 Entrez Gene: 5019 Ensembl: ENSG00000083720 UCSC: uc003jmn.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
5p13	chr5:28900000-42500000	3 (1/1/1)

Gene related GO terms (count: 21)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0042803	protein homodimerization activity	Molecular Function	NAS[10964512]	113
GO:0042594	response to starvation	Biological Process		6
GO:0042493	response to drug	Biological Process		68
GO:0042182	ketone catabolic process	Biological Process		1
GO:0032024	positive regulation of insulin secretion	Biological Process		5
GO:0014823	response to activity	Biological Process		7
GO:0009725	response to hormone stimulus	Biological Process		11
GO:0008260	3-oxoacid CoA-transferase activity	Molecular Function	IMP[10964512]	1
GO:0071333	cellular response to glucose stimulus	Biological Process		8
GO:0071229	cellular response to acid	Biological Process		1
GO:0060612	adipose tissue development	Biological Process		7
GO:0046952	ketone body catabolic process	Biological Process		2
GO:0046950	cellular ketone body metabolic process	Biological Process	IMP[9671268]	2
GO:0045471	response to ethanol	Biological Process		17
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0044255	cellular lipid metabolic process	Biological Process		30
GO:0007507	heart development	Biological Process		23
GO:0007584	response to nutrient	Biological Process		15
GO:0005759	mitochondrial matrix	Cellular Component		32
GO:0007420	brain development	Biological Process		33
GO:0005739	mitochondrion	Cellular Component	NAS[10964512]	183

Gene related KEGG pathways (count: 3)

ID	Name	No. of Genes in ADHDgene
hsa00650	Butanoate metabolism	9
hsa00280	Valine, leucine and isoleucine degradation	7
hsa00072	Synthesis and degradation of ketone bodies	2

Genes shared at least 5 GO terms with OXCT1 (count: 5)

Gene Symbol	Pathway Count	Pathway List
ACAT1	11	protein homodimerization activity; response to starvation; response to hormone stimulus; adipose tissue development; ketone body catabolic process; cellular ketone body metabolic process; small molecule metabolic process; cellular lipid metabolic process; mitochondrial matrix; brain development; mitochondrion;
AACS	7	response to starvation; response to drug; positive regulation of insulin secretion; cellular response to glucose stimulus; adipose tissue development; response to ethanol; response to nutrient;
TH	6	response to activity; cellular response to glucose stimulus; response to ethanol; small molecule metabolic process; heart development; mitochondrion;
UGT1A1	5	protein homodimerization activity; response to starvation; response to drug; small molecule metabolic process; response to nutrient;
NCOA6	5	response to hormone stimulus; small molecule metabolic process; cellular lipid metabolic process; heart development; brain development;

Genes shared at least 2 KEGG pathways with OXCT1 (count: 2)

Gene Symbol	Pathway Count	Pathway List
ACAT1	3	Butanoate metabolism; Valine, leucine and isoleucine degradation; Synthesis and degradation of ketone bodies;
ECHS1	2	Butanoate metabolism; Valine, leucine and isoleucine degradation;

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Region: chr5:41730167..41870791 View in gBrowse