ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005509
Name calcium ion binding
Type molecular function
No. of Genes in ADHDgene  140
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 140)

Literature-origin genes (count: 17)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
PLCL1 phospholipase C-like 1 2q33 1(0/0/1) IEA
SYT2 synaptotagmin II 1q32.1 1(1/0/0) IEA
KCNIP4 Kv channel interacting protein 4 4p15.32 1(1/0/0) IEA
SLIT1 slit homolog 1 (Drosophila) 10q23.3-q24 1(0/0/1) NAS[9813312]
NCAN neurocan 19p12 1(0/1/0) IEA
MMP24 matrix metallopeptidase 24 (membrane-inserted) 20q11.2 1(0/0/1) IEA
CDH13 cadherin 13 16q23.3 4(1/2/1) IEA
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IDA[11850416]
GRM7 glutamate receptor, metabotropic 7 3p26-p25 3(2/1/0) IDA[18599484]
LRP1B low density lipoprotein receptor-related protein 1B 2q21.2 1(0/1/0) IEA
SYP synaptophysin Xp11.23-p11.22 4(4/0/0) NAS
SYT1 synaptotagmin I 12q21.2 4(2/2/0) IEA
CDH23 cadherin-related 23 10q22.1 1(0/1/0) IEA
NUCB1 nucleobindin 1 19q13.33 1(0/0/1) IEA
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 4q32.3 1(1/0/0) IEA
MCTP1 multiple C2 domains, transmembrane 1 5q15 1(0/1/0) IDA[15528213]
TLL2 tolloid-like 2 10q23-q24 1(0/0/1) IEA

Genes from other sources Help (count: 123)

Approved Symbol Approved Name Source Evidence[PMID]
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) Mapped by significant region IEA
RYR2 ryanodine receptor 2 (cardiac) Mapped by CNV; Mapped by PBA pathway IEA
SYT7 synaptotagmin VII Mapped by significant region IEA
NECAB2 N-terminal EF-hand calcium binding protein 2 Mapped by CNV; Mapped by significant region IEA
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) Mapped by CNV IEA
DSG4 desmoglein 4 Mapped by significant region IEA
CCBE1 collagen and calcium binding EGF domains 1 Mapped by significant region IEA
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) Mapped by significant region NAS[10918068]; TAS[9789079]
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Mapped by significant region TAS[16130169]
DGKG diacylglycerol kinase, gamma 90kDa Mapped by Literature SNP IEA
CLSTN2 calsyntenin 2 Mapped by CNV IEA
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 Mapped by significant region IEA
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 Mapped by Literature SNP IEA
CDH19 cadherin 19, type 2 Mapped by LD-proxy; Mapped by CNV IEA
DCHS1 dachsous cadherin-related 1 Mapped by CNV IEA
UMOD uromodulin Mapped by significant region IEA
PLA2G3 phospholipase A2, group III Mapped by PBA pathway IEA
PLA2G10 phospholipase A2, group X Mapped by significant region; Mapped by PBA pathway IEA
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle Mapped by CNV IEA
PNLIPRP1 pancreatic lipase-related protein 1 Mapped by PBA pathway ISS
DSG2 desmoglein 2 Mapped by significant region IEA
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 Mapped by LD-proxy TAS[2446322]
DSC2 desmocollin 2 Mapped by significant region IEA
RYR3 ryanodine receptor 3 Mapped by CNV; Mapped by PBA pathway IEA
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 Mapped by CNV IEA
ACTN3 actinin, alpha 3 (gene/pseudogene) Mapped by significant region IEA
CABP4 calcium binding protein 4 Mapped by significant region NAS[16960802]; TAS[15452577]
CUBN cubilin (intrinsic factor-cobalamin receptor) Mapped by CNV IEA
LPCAT4 lysophosphatidylcholine acyltransferase 4 Mapped by CNV IEA
CDH2 cadherin 2, type 1, N-cadherin (neuronal) Mapped by significant region IEA
NKD2 naked cuticle homolog 2 (Drosophila) Mapped by significant region IEA
STIM2 stromal interaction molecule 2 Mapped by CNV IDA[18166150]
REPS2 RALBP1 associated Eps domain containing 2 Mapped by CNV IEA
PLCD1 phospholipase C, delta 1 Mapped by PBA pathway IEA
PCDH7 protocadherin 7 Mapped by CNV IEA
EYS eyes shut homolog (Drosophila) Mapped by significant region IEA
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase Mapped by significant region IEA
CDH4 cadherin 4, type 1, R-cadherin (retinal) Mapped by CNV IEA
PLA2G5 phospholipase A2, group V Mapped by PBA pathway IEA
HPCAL1 hippocalcin-like 1 Mapped by significant region IEA
CABP2 calcium binding protein 2 Mapped by significant region IEA
F10 coagulation factor X Mapped by CNV IEA
PLCD4 phospholipase C, delta 4 Mapped by significant region IEA
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) Mapped by significant region IEA
F7 coagulation factor VII (serum prothrombin conversion accelerator) Mapped by CNV IEA
CDHR1 cadherin-related family member 1 Mapped by CNV IEA
MMP10 matrix metallopeptidase 10 (stromelysin 2) Mapped by significant region IEA
PPP3R2 protein phosphatase 3, regulatory subunit B, beta Mapped by significant region IEA
DSG3 desmoglein 3 Mapped by significant region IEA
PLA2G2D phospholipase A2, group IID Mapped by PBA pathway IEA
PLCH1 phospholipase C, eta 1 Mapped by PBA pathway IEA
ASPN asporin Mapped by significant region IDA[19589127]
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated Mapped by significant region IDA[11820818]
LPCAT1 lysophosphatidylcholine acyltransferase 1 Mapped by LD-proxy; Mapped by significant region IEA
CANX calnexin Mapped by CNV IEA
GSN gelsolin Mapped by significant region; Mapped by PBA pathway TAS[1321812]
VWCE von Willebrand factor C and EGF domains Mapped by significant region IEA
LTBP1 latent transforming growth factor beta binding protein 1 Mapped by CNV IEA
MMP27 matrix metallopeptidase 27 Mapped by significant region IEA
MMP1 matrix metallopeptidase 1 (interstitial collagenase) Mapped by significant region IEA
MMP25 matrix metallopeptidase 25 Mapped by significant region IEA
MAN1A1 mannosidase, alpha, class 1A, member 1 Mapped by significant region IEA
CRB2 crumbs family member 2 Mapped by significant region IEA
CDHR5 cadherin-related family member 5 Mapped by LD-proxy ISS
DSC3 desmocollin 3 Mapped by significant region IEA
DNASE1L2 deoxyribonuclease I-like 2 Mapped by significant region TAS[9205125]
MMP13 matrix metallopeptidase 13 (collagenase 3) Mapped by significant region IEA
CD248 CD248 molecule, endosialin Mapped by significant region IEA
NELL1 NEL-like 1 (chicken) Mapped by CNV IEA
DSC1 desmocollin 1 Mapped by significant region IEA
MEGF9 multiple EGF-like-domains 9 Mapped by significant region NAS
CAPN1 calpain 1, (mu/I) large subunit Mapped by significant region IEA
MMP11 matrix metallopeptidase 11 (stromelysin 3) Mapped by CNV IEA
SYNRG synergin, gamma Mapped by CNV IEA
MICU2 mitochondrial calcium uptake 2 Mapped by significant region IEA
CDH15 cadherin 15, type 1, M-cadherin (myotubule) Mapped by CNV; Mapped by significant region IEA
PLA2G2E phospholipase A2, group IIE Mapped by PBA pathway IEA
SYT4 synaptotagmin IV Mapped by significant region IEA
MMP16 matrix metallopeptidase 16 (membrane-inserted) Mapped by CNV IEA
VIL1 villin 1 Mapped by significant region IDA[11500485]
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 Mapped by CNV IEA
PLCE1 phospholipase C, epsilon 1 Mapped by PBA pathway IEA
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 Mapped by significant region IEA
MMP20 matrix metallopeptidase 20 Mapped by significant region IEA
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) Mapped by PBA pathway IEA
DUOX2 dual oxidase 2 Mapped by CNV IDA[15972824]
KCNIP1 Kv channel interacting protein 1 Mapped by Literature SNP IEA
DTNA dystrobrevin, alpha Mapped by significant region IEA
EHD3 EH-domain containing 3 Mapped by CNV IEA
ADAM8 ADAM metallopeptidase domain 8 Mapped by LD-proxy; Mapped by CNV ISS
MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) Mapped by significant region IEA
PLA2G1B phospholipase A2, group IB (pancreas) Mapped by PBA pathway IDA[7060561]
PDCD6 programmed cell death 6 Mapped by significant region ISS
CAPN14 calpain 14 Mapped by CNV IEA
DSG1 desmoglein 1 Mapped by significant region NAS[1770008]
MMP12 matrix metallopeptidase 12 (macrophage elastase) Mapped by significant region IEA
CALN1 calneuron 1 Mapped by CNV IEA
RAB11FIP3 RAB11 family interacting protein 3 (class II) Mapped by significant region IEA
CDH9 cadherin 9, type 2 (T1-cadherin) Mapped by significant region IEA
MMP8 matrix metallopeptidase 8 (neutrophil collagenase) Mapped by significant region IEA
PLA2G4B phospholipase A2, group IVB (cytosolic) Mapped by PBA pathway NAS[10085124]
CAPSL calcyphosine-like Mapped by significant region IEA
CHP2 calcineurin-like EF-hand protein 2 Mapped by significant region IDA
CDH12 cadherin 12, type 2 (N-cadherin 2) Mapped by CNV; Mapped by significant region IEA
EEF2K eukaryotic elongation factor-2 kinase Mapped by CNV; Mapped by significant region IEA
EFCAB5 EF-hand calcium binding domain 5 Mapped by LD-proxy IEA
PLCB2 phospholipase C, beta 2 Mapped by PBA pathway IEA
RHOT2 ras homolog family member T2 Mapped by significant region IEA
RYR1 ryanodine receptor 1 (skeletal) Mapped by PBA pathway IEA
EHD1 EH-domain containing 1 Mapped by significant region IEA
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 Mapped by Literature SNP IMP[9405806]; ISS
SUSD1 sushi domain containing 1 Mapped by significant region IEA
TLL1 tolloid-like 1 Mapped by Literature SNP IEA
CDH10 cadherin 10, type 2 (T2-cadherin) Mapped by significant region IEA
PKD1L2 polycystic kidney disease 1-like 2 Mapped by significant region IEA
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) Mapped by significant region IEA
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa Mapped by significant region NAS[10234612]
CDH18 cadherin 18, type 2 Mapped by significant region IEA
PNLIPRP2 pancreatic lipase-related protein 2 Mapped by PBA pathway IDA[18702514]
LTBP3 latent transforming growth factor beta binding protein 3 Mapped by significant region IEA
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 Mapped by significant region IEA
DUOX1 dual oxidase 1 Mapped by CNV IEA
FAT3 FAT atypical cadherin 3 Mapped by significant region IEA

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014