ADHDgene Database

Gene Report

Basic Info

Approved Symbol	STIM2
Approved Name	stromal interaction molecule 2
Location	4p15.2
Position	chr4:26859300-27027003, +
External Links	HGNC: 19205 Entrez Gene: 57620 Ensembl: ENSG00000109689 UCSC: uc003gsg.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 2)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_33	chr4:26350218-27635050 (NCBI Build 36.1 (hg18))	1234728	4p15.2	Gain	Paternal
CNV_Williams[2010]_18	chr4:23596065-27014659 (NCBI Build 36.1 (hg18))	3365040	4p15.2	Gain

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005886	plasma membrane	Cellular Component	IDA[18160041]	772
GO:0005789	endoplasmic reticulum membrane	Cellular Component		140
GO:0005783	endoplasmic reticulum	Cellular Component	IDA[18160041]	100
GO:0005515	protein binding	Molecular Function	IPI[11463338]	910
GO:0005509	calcium ion binding	Molecular Function	IDA[18166150]	124
GO:0005246	calcium channel regulator activity	Molecular Function	IMP[18160041]	10
GO:0051928	positive regulation of calcium ion transport	Biological Process	IDA[17905723]; IMP[18160041]	6
GO:0006874	cellular calcium ion homeostasis	Biological Process	IMP[18160041]	16
GO:0015279	store-operated calcium channel activity	Molecular Function	IDA[16860747]	7
GO:0016021	integral to membrane	Cellular Component		845
GO:0032237	activation of store-operated calcium channel activity	Biological Process	IDA[17905723]; IMP[18160041]	2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with STIM2 (count: 3)

Gene Symbol	Pathway Count	Pathway List
ATP10A	5	plasma membrane; endoplasmic reticulum membrane; endoplasmic reticulum; protein binding; integral to membrane;
TMED10	5	plasma membrane; endoplasmic reticulum membrane; endoplasmic reticulum; protein binding; integral to membrane;
TRPC6	5	plasma membrane; protein binding; positive regulation of calcium ion transport; store-operated calcium channel activity; integral to membrane;

Genes shared at least 2 KEGG pathways with STIM2 (count: 0)

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Region: chr4:26859300..27027003 View in gBrowse