ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PLCH1
Previous Symbol	PLCL3
Symbol Alias	KIAA1069, MGC117152, DKFZp434C1372, PLCeta1
Approved Name	phospholipase C, eta 1
Previous Name	phospholipase C-like 3
Location	3q25
Position	chr3:155093369-155462856, -
External Links	HGNC: 29185 Entrez Gene: 23007 Ensembl: ENSG00000114805 UCSC: uc011bok.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0016298	lipase activity	Molecular Function		49

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005543	phospholipid binding	Molecular Function		61
GO:0005509	calcium ion binding	Molecular Function		124
GO:0004871	signal transducer activity	Molecular Function		49
GO:0004435	phosphatidylinositol phospholipase C activity	Molecular Function		20
GO:0016042	lipid catabolic process	Biological Process		32
GO:0005829	cytosol	Cellular Component		447
GO:0005737	cytoplasm	Cellular Component	IDA[15702972]	690
GO:0050429	calcium-dependent phospholipase C activity	Molecular Function	IDA[15702972]	1
GO:0048015	phosphatidylinositol-mediated signaling	Biological Process	IDA[15702972]	16
GO:0043231	intracellular membrane-bounded organelle	Cellular Component		62
GO:0031965	nuclear membrane	Cellular Component		27

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PLCH1 (count: 6)

Gene Symbol	Pathway Count	Pathway List
PLCD1	8	phospholipid binding; calcium ion binding; signal transducer activity; phosphatidylinositol phospholipase C activity; lipase activity; lipid catabolic process; cytosol; cytoplasm;
PLCB2	6	calcium ion binding; signal transducer activity; phosphatidylinositol phospholipase C activity; lipase activity; lipid catabolic process; cytosol;
PLCE1	6	calcium ion binding; phosphatidylinositol phospholipase C activity; lipase activity; lipid catabolic process; cytosol; cytoplasm;
PLCD4	5	phospholipid binding; calcium ion binding; signal transducer activity; phosphatidylinositol phospholipase C activity; lipid catabolic process;
PLCL1	5	phospholipid binding; calcium ion binding; signal transducer activity; phosphatidylinositol phospholipase C activity; cytoplasm;
PLCB3	5	calcium ion binding; signal transducer activity; phosphatidylinositol phospholipase C activity; lipid catabolic process; cytosol;

Genes shared at least 2 KEGG pathways with PLCH1 (count: 0)

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Region: chr3:155093369..155462856 View in gBrowse