ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MMP13
Symbol Alias	CLG3
Approved Name	matrix metallopeptidase 13 (collagenase 3)
Previous Name	matrix metalloproteinase 13 (collagenase 3)
Name Alias	collagenase 3
Location	11q22.3
Position	chr11:102813721-102826463, -
External Links	HGNC: 7159 Entrez Gene: 4322 Ensembl: ENSG00000137745 UCSC: uc001phl.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)
11q22	chr11:97200000-110400000	1 (1/0/0)

Gene related GO terms (count: 13)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0044267	cellular protein metabolic process	Biological Process		64
GO:0030574	collagen catabolic process	Biological Process		10
GO:0051216	cartilage development	Biological Process		11
GO:0005615	extracellular space	Cellular Component	TAS[8207000]	126
GO:0006508	proteolysis	Biological Process		102
GO:0005576	extracellular region	Cellular Component		240
GO:0005578	proteinaceous extracellular matrix	Cellular Component		47
GO:0030198	extracellular matrix organization	Biological Process		31
GO:0030282	bone mineralization	Biological Process		5
GO:0008270	zinc ion binding	Molecular Function		323
GO:0022617	extracellular matrix disassembly	Biological Process		14
GO:0004222	metalloendopeptidase activity	Molecular Function		33
GO:0005509	calcium ion binding	Molecular Function		124

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MMP13 (count: 19)

Gene Symbol	Pathway Count	Pathway List
MMP10	10	collagen catabolic process; extracellular space; proteolysis; extracellular region; proteinaceous extracellular matrix; extracellular matrix organization; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding;
MMP3	10	collagen catabolic process; extracellular space; proteolysis; extracellular region; proteinaceous extracellular matrix; extracellular matrix organization; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding;
MMP8	10	collagen catabolic process; extracellular space; proteolysis; extracellular region; proteinaceous extracellular matrix; extracellular matrix organization; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding;
MMP1	9	collagen catabolic process; proteolysis; extracellular region; proteinaceous extracellular matrix; extracellular matrix organization; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding;
MMP11	9	collagen catabolic process; proteolysis; extracellular region; proteinaceous extracellular matrix; extracellular matrix organization; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding;
MMP7	9	collagen catabolic process; extracellular space; proteolysis; extracellular region; proteinaceous extracellular matrix; extracellular matrix organization; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity;
MMP16	8	collagen catabolic process; proteolysis; proteinaceous extracellular matrix; extracellular matrix organization; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding;
ADAMTS2	7	collagen catabolic process; proteolysis; extracellular region; proteinaceous extracellular matrix; extracellular matrix organization; zinc ion binding; metalloendopeptidase activity;
MMP27	6	collagen catabolic process; proteolysis; proteinaceous extracellular matrix; zinc ion binding; metalloendopeptidase activity; calcium ion binding;
MMP20	6	extracellular space; proteolysis; proteinaceous extracellular matrix; zinc ion binding; metalloendopeptidase activity; calcium ion binding;
TLL1	6	proteolysis; extracellular region; extracellular matrix organization; zinc ion binding; metalloendopeptidase activity; calcium ion binding;
F7	5	cellular protein metabolic process; extracellular space; proteolysis; extracellular region; calcium ion binding;
FURIN	5	cellular protein metabolic process; extracellular space; proteolysis; extracellular matrix organization; extracellular matrix disassembly;
CTRB1	5	extracellular space; proteolysis; extracellular region; extracellular matrix organization; extracellular matrix disassembly;
CTRB2	5	extracellular space; proteolysis; extracellular region; extracellular matrix organization; extracellular matrix disassembly;
CTSG	5	extracellular space; proteolysis; extracellular region; extracellular matrix organization; extracellular matrix disassembly;
MMP12	5	proteolysis; proteinaceous extracellular matrix; zinc ion binding; metalloendopeptidase activity; calcium ion binding;
MMP24	5	proteolysis; proteinaceous extracellular matrix; zinc ion binding; metalloendopeptidase activity; calcium ion binding;
TLL2	5	proteolysis; extracellular region; zinc ion binding; metalloendopeptidase activity; calcium ion binding;

Genes shared at least 2 KEGG pathways with MMP13 (count: 0)

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Region: chr11:102813721..102826463 View in gBrowse