ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CTRB2
Approved Name	chymotrypsinogen B2
Location	16q22.3
Position	chr16:75237994-75241083, -1
External Links	HGNC: 2522 Entrez Gene: 440387 Ensembl: ENSG00000168928 UCSC: uc002fdr.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16q23.1-24.3	chr16:74100000-90354753	1 (1/0/0)

Gene related GO terms (count: 7)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0004252	serine-type endopeptidase activity	molecular function	IEA	40
GO:0006508	proteolysis	biological process	IEA	123
GO:0007586	digestion	biological process	IEA	13
GO:0022617	extracellular matrix disassembly	biological process	TAS	16
GO:0030198	extracellular matrix organization	biological process	TAS	32
GO:0005615	extracellular space	cellular component	IEA	133
GO:0005576	extracellular region	cellular component	TAS	267

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CTRB2 (count: 10)

Gene Symbol	Pathway Count	Pathway List
CTRB1	7	serine-type endopeptidase activity; proteolysis; digestion; extracellular matrix disassembly; extracellular matrix organization; extracellular space; extracellular region;
TPSAB1	6	serine-type endopeptidase activity; proteolysis; extracellular matrix disassembly; extracellular matrix organization; extracellular space; extracellular region;
CTSG	6	serine-type endopeptidase activity; proteolysis; extracellular matrix disassembly; extracellular matrix organization; extracellular space; extracellular region;
MMP8	6	serine-type endopeptidase activity; proteolysis; extracellular matrix disassembly; extracellular matrix organization; extracellular space; extracellular region;
CMA1	5	serine-type endopeptidase activity; proteolysis; extracellular matrix disassembly; extracellular matrix organization; extracellular region;
FURIN	5	serine-type endopeptidase activity; proteolysis; extracellular matrix disassembly; extracellular matrix organization; extracellular space;
MMP10	5	proteolysis; extracellular matrix disassembly; extracellular matrix organization; extracellular space; extracellular region;
MMP7	5	proteolysis; extracellular matrix disassembly; extracellular matrix organization; extracellular space; extracellular region;
MMP13	5	proteolysis; extracellular matrix disassembly; extracellular matrix organization; extracellular space; extracellular region;
MMP3	5	proteolysis; extracellular matrix disassembly; extracellular matrix organization; extracellular space; extracellular region;

Genes shared at least 2 KEGG pathways with CTRB2 (count: 0)

View in gBrowse

Region: chr16:75237994..75241083 View in gBrowse