ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0022617
Name extracellular matrix disassembly
Type biological process
No. of Genes in ADHDgene  16
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 16)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MMP7 matrix metallopeptidase 7 (matrilysin, uterine) 11q21-q22 1(0/0/1) TAS
FURIN furin (paired basic amino acid cleaving enzyme) 15q26.1 1(0/0/1) TAS

Genes from other sources Help (count: 14)

Approved Symbol Approved Name Source Evidence[PMID]
MMP1 matrix metallopeptidase 1 (interstitial collagenase) Mapped by significant region TAS
CTRB1 chymotrypsinogen B1 Mapped by significant region TAS
CMA1 chymase 1, mast cell Mapped by significant region TAS
MMP16 matrix metallopeptidase 16 (membrane-inserted) Mapped by CNV TAS
MMP8 matrix metallopeptidase 8 (neutrophil collagenase) Mapped by significant region TAS
MMP13 matrix metallopeptidase 13 (collagenase 3) Mapped by significant region TAS
LAMC1 laminin, gamma 1 (formerly LAMB2) Mapped by significant region IMP[15159456]
MMP11 matrix metallopeptidase 11 (stromelysin 3) Mapped by CNV TAS
CTRB2 chymotrypsinogen B2 Mapped by significant region TAS
MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) Mapped by significant region TAS
TPSAB1 tryptase alpha/beta 1 Mapped by significant region TAS
CTSG cathepsin G Mapped by significant region TAS
NOXO1 NADPH oxidase organizer 1 Mapped by significant region IMP[19755710]
MMP10 matrix metallopeptidase 10 (stromelysin 2) Mapped by significant region TAS