ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	F7
Approved Name	coagulation factor VII (serum prothrombin conversion accelerator)
Name Alias	"eptacog alfa", "FVII coagulation protein", "factor VII"
Location	13q34
Position	chr13:113760105-113774995, 1
External Links	HGNC: 3544 Entrez Gene: 2155 Ensembl: ENSG00000057593 UCSC: uc001vsv.4
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_155	chr13:112336427-112835822 (NCBI Build 35 (hg17))	499396	13q34	Duplication	Maternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 29)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 29)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0007623	circadian rhythm	biological process	IEA	15
GO:0008236	serine-type peptidase activity	molecular function	TAS[3037537]	16
GO:0050927	positive regulation of positive chemotaxis	biological process	IDA[17991872]	3
GO:0031982	vesicle	cellular component	IEA	6
GO:0005102	receptor binding	molecular function	IEA	64
GO:0043627	response to estrogen stimulus	biological process	IEA	11
GO:0043687	post-translational protein modification	biological process	TAS	42
GO:0005886	plasma membrane	cellular component	TAS	839
GO:0007596	blood coagulation	biological process	TAS	85
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	biological process	IDA[17991872]	1
GO:0005615	extracellular space	cellular component	IEA	133
GO:0005576	extracellular region	cellular component	TAS	267
GO:0007598	blood coagulation, extrinsic pathway	biological process	TAS	2
GO:0004252	serine-type endopeptidase activity	molecular function	IEA	40
GO:0051897	positive regulation of protein kinase B signaling cascade	biological process	IDA[18612547]	17
GO:0030335	positive regulation of cell migration	biological process	TAS[18612547]	28
GO:0031100	organ regeneration	biological process	IEA	11
GO:0005796	Golgi lumen	cellular component	TAS	14
GO:0030194	positive regulation of blood coagulation	biological process	IEA	1
GO:0043066	negative regulation of apoptotic process	biological process	TAS[18612547]	85
GO:0005509	calcium ion binding	molecular function	IEA	140
GO:0017187	peptidyl-glutamic acid carboxylation	biological process	TAS	4
GO:0032571	response to vitamin K	biological process	IEA	1
GO:0060416	response to growth hormone stimulus	biological process	IEA	2
GO:0002690	positive regulation of leukocyte chemotaxis	biological process	IDA[17991872]	3
GO:0005788	endoplasmic reticulum lumen	cellular component	TAS	35
GO:0044267	cellular protein metabolic process	biological process	TAS	78
GO:0001948	glycoprotein binding	molecular function	IPI[3455766]	3
GO:0006508	proteolysis	biological process	TAS	123

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04610	Complement and coagulation cascades	11

Genes shared at least 5 GO terms with F7 (count: 16)

Gene Symbol	Pathway Count	Pathway List
F10	14	post-translational protein modification; plasma membrane; blood coagulation; extracellular region; blood coagulation, extrinsic pathway; serine-type endopeptidase activity; positive regulation of protein kinase B signaling cascade; positive regulation of cell migration; Golgi lumen; calcium ion binding; peptidyl-glutamic acid carboxylation; endoplasmic reticulum lumen; cellular protein metabolic process; proteolysis;
FURIN	8	post-translational protein modification; plasma membrane; extracellular space; serine-type endopeptidase activity; Golgi lumen; peptidyl-glutamic acid carboxylation; cellular protein metabolic process; proteolysis;
APOA1	7	response to estrogen stimulus; plasma membrane; blood coagulation; extracellular space; extracellular region; organ regeneration; endoplasmic reticulum lumen;
INS	7	extracellular space; extracellular region; positive regulation of protein kinase B signaling cascade; positive regulation of cell migration; Golgi lumen; negative regulation of apoptotic process; endoplasmic reticulum lumen;
PRSS8	6	serine-type peptidase activity; plasma membrane; extracellular space; extracellular region; serine-type endopeptidase activity; proteolysis;
VEGFA	6	positive regulation of positive chemotaxis; blood coagulation; extracellular space; extracellular region; positive regulation of cell migration; negative regulation of apoptotic process;
TPSAB1	5	serine-type peptidase activity; extracellular space; extracellular region; serine-type endopeptidase activity; proteolysis;
ST14	5	serine-type peptidase activity; plasma membrane; extracellular region; serine-type endopeptidase activity; proteolysis;
CDH13	5	positive regulation of positive chemotaxis; plasma membrane; extracellular space; positive regulation of cell migration; calcium ion binding;
SEMA4D	5	receptor binding; plasma membrane; extracellular space; positive regulation of cell migration; negative regulation of apoptotic process;
EDEM2	5	post-translational protein modification; extracellular region; calcium ion binding; endoplasmic reticulum lumen; cellular protein metabolic process;
CTSG	5	plasma membrane; extracellular space; extracellular region; serine-type endopeptidase activity; proteolysis;
VEGFB	5	blood coagulation; extracellular space; extracellular region; positive regulation of protein kinase B signaling cascade; negative regulation of apoptotic process;
IL6	5	extracellular space; extracellular region; positive regulation of protein kinase B signaling cascade; negative regulation of apoptotic process; positive regulation of leukocyte chemotaxis;
MMP8	5	extracellular space; extracellular region; serine-type endopeptidase activity; calcium ion binding; proteolysis;
MMP13	5	extracellular space; extracellular region; calcium ion binding; cellular protein metabolic process; proteolysis;

Genes shared at least 2 KEGG pathways with F7 (count: 0)

View in gBrowse

Region: chr13:113760105..113774995 View in gBrowse