ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0008284
Name	positive regulation of cell proliferation
Type	Biological Process
No. of Genes in ADHDgene	69
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 69)

Literature-origin genes (count: 15)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
ADRA2A	adrenergic, alpha-2A-, receptor	10q24-q26	12(4/8/0)	TAS[10896916]
EREG	epiregulin	4q21.21	1(0/0/1)	IDA[10681561]
ADRA1D	adrenergic, alpha-1D-, receptor	20p13	1(0/1/0)	TAS[10860850]
NTF3	neurotrophin 3	12p13	3(1/2/0)
CHRNA7	cholinergic receptor, nicotinic, alpha 7	15q13.3	2(0/1/1)	IMP[17498763]
HTR4	5-hydroxytryptamine (serotonin) receptor 4	5q31-q33	1(1/0/0)	IMP[15925089]
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	5q11.2-q13	1(1/0/0)	TAS[1330092]
DRD3	dopamine receptor D3	3q13.3	8(1/7/0)
CNTFR	ciliary neurotrophic factor receptor	9p13	1(1/0/0)
HES1	hairy and enhancer of split 1, (Drosophila)	3q28-q29	1(1/0/0)
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	9q22.1	1(1/0/0)
VEGFA	vascular endothelial growth factor A	6p12	1(0/1/0)	IDA[7929439]
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	13q14-q21	12(6/6/0)
CNTF	ciliary neurotrophic factor	11q12	1(1/0/0)
ISL1	ISL LIM homeobox 1	5q11.2	1(0/1/0)

Genes from other sources (count: 54)

Approved Symbol	Approved Name	Source	Evidence[PMID]
TNFSF4	tumor necrosis factor (ligand) superfamily, member 4	Mapped by significant region	TAS[7913952]
CTF1	cardiotrophin 1	Mapped by CNV	TAS[7862649]
GAB2	GRB2-associated binding protein 2	Mapped by significant region	IDA[19172738]
IL6	interleukin 6 (interferon, beta 2)	Mapped by significant region	IDA[2261637]; IMP[18719127]
S1PR3	sphingosine-1-phosphate receptor 3	Mapped by significant region	TAS[10617617]
HOXA3	homeobox A3	Mapped by significant region
CCKBR	cholecystokinin B receptor	Mapped by CNV; Mapped by PBA pathway	IDA[10913157]
TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	Mapped by significant region	TAS[9806637]
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	Mapped by significant region
TGFBR1	transforming growth factor, beta receptor 1	Mapped by significant region	IMP[14633705]
FOSL1	FOS-like antigen 1	Mapped by significant region	TAS[8230424]
YAP1	Yes-associated protein 1	Mapped by significant region
TNC	tenascin C	Mapped by significant region
ALDH3A1	aldehyde dehydrogenase 3 family, member A1	Mapped by significant region
RPS15A	ribosomal protein S15a	Mapped by significant region	IDA[15108328]
FGF9	fibroblast growth factor 9 (glia-activating factor)	Mapped by significant region	IDA[8321227]
CDC25B	cell division cycle 25 homolog B (S. pombe)	Mapped by CNV	TAS[8276402]
CXCR2	chemokine (C-X-C motif) receptor 2	Mapped by significant region	IDA[10438939]
BTC	betacellulin	Mapped by CNV
LIFR	leukemia inhibitory factor receptor alpha	Mapped by significant region	IDA[8999038]
TBX1	T-box 1	Mapped by CNV
RPS9	ribosomal protein S9	Mapped by CNV	IMP[18420587]
ACER3	alkaline ceramidase 3	Mapped by significant region
EDNRA	endothelin receptor type A	Mapped by PBA pathway
FGF4	fibroblast growth factor 4	Mapped by significant region	IGI[8663044]
GREM1	gremlin 1	Mapped by CNV; Mapped by significant region	IDA[16545136]
INS	insulin	Mapped by literature SNP	IDA[17925406]
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mapped by significant region
CDCA7L	cell division cycle associated 7-like	Mapped by significant region	IDA[15994933]
REG1A	regenerating islet-derived 1 alpha	Mapped by CNV	TAS[2332435]
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	Mapped by CNV	TAS[9367155]
CIAO1	cytosolic iron-sulfur protein assembly 1	Mapped by LD-proxy	TAS[9556563]
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy
ODC1	ornithine decarboxylase 1	Mapped by significant region
LRP5	low density lipoprotein receptor-related protein 5	Mapped by CNV; Mapped by significant region	IDA[9790987]
FGF3	fibroblast growth factor 3	Mapped by significant region	IGI[8663044]
CAV3	caveolin 3	Mapped by LD-proxy; Mapped by literature SNP
CHRM1	cholinergic receptor, muscarinic 1	Mapped by PBA pathway; Mapped by significant region	TAS[2739737]
BIRC6	baculoviral IAP repeat containing 6	Mapped by CNV
IGF2	insulin-like growth factor 2 (somatomedin A)	Mapped by LD-proxy; Mapped by literature SNP	IC[11500939]
FLT4	fms-related tyrosine kinase 4	Mapped by CNV	IGI[11574540]; IMP[19779139]
CLCF1	cardiotrophin-like cytokine factor 1	Mapped by significant region	IDA[11285233]
FGF19	fibroblast growth factor 19	Mapped by significant region	IGI[18187602]
PDCD10	programmed cell death 10	Mapped by CNV	IDA[17360971]
CTGF	connective tissue growth factor	Mapped by significant region
CAPN1	calpain 1, (mu/I) large subunit	Mapped by significant region	TAS[8702541]
MTA3	metastasis associated 1 family, member 3	Mapped by LD-proxy; Mapped by literature SNP
ADAM17	ADAM metallopeptidase domain 17	Mapped by significant region	IMP[18373975]
SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)	Mapped by CNV
ILK	integrin-linked kinase	Mapped by CNV
MVD	mevalonate (diphospho) decarboxylase	Mapped by significant region	IMP[9270019]
OSMR	oncostatin M receptor	Mapped by significant region	IGI[8999038]
TTK	TTK protein kinase	Mapped by PBA pathway	TAS[1639825]
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	Mapped by significant region