ADHDgene Database

Gene Report

Basic Info

Approved Symbol	ACER3
Previous Symbol	PHCA
Symbol Alias	FLJ11238, APHC
Approved Name	alkaline ceramidase 3
Previous Name	phytoceramidase, alkaline
Name Alias	alkaline phytoceramidase
Location	11q13.5
Position	chr11:76571911-76737841, +
External Links	HGNC: 16066 Entrez Gene: 55331 Ensembl: ENSG00000078124 UCSC: uc009yum.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0071602	phytosphingosine biosynthetic process	Biological Process		1
GO:0070774	phytoceramidase activity	Molecular Function		1
GO:0005789	endoplasmic reticulum membrane	Cellular Component		140
GO:0006644	phospholipid metabolic process	Biological Process		59
GO:0006665	sphingolipid metabolic process	Biological Process		16
GO:0006672	ceramide metabolic process	Biological Process		1
GO:0008284	positive regulation of cell proliferation	Biological Process		69
GO:0030148	sphingolipid biosynthetic process	Biological Process		4
GO:0030173	integral to Golgi membrane	Cellular Component	IDA[11356846]	8
GO:0030176	integral to endoplasmic reticulum membrane	Cellular Component	IDA[11356846]	14
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0046512	sphingosine biosynthetic process	Biological Process		2

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00600	Sphingolipid metabolism	10

Genes shared at least 5 GO terms with ACER3 (count: 2)

Gene Symbol	Pathway Count	Pathway List
SPTLC1	6	endoplasmic reticulum membrane; phospholipid metabolic process; sphingolipid metabolic process; sphingolipid biosynthetic process; small molecule metabolic process; sphingosine biosynthetic process;
SPTLC3	5	endoplasmic reticulum membrane; phospholipid metabolic process; sphingolipid metabolic process; sphingolipid biosynthetic process; small molecule metabolic process;

Genes shared at least 2 KEGG pathways with ACER3 (count: 0)

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Region: chr11:76571911..76737841 View in gBrowse