ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa03040
Name Spliceosome
Description  After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified.
No. of Genes in ADHDgene  47
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 47)

Literature-origin genes (count: 0)

Genes from other sources Help(count: 47)

Approved Symbol Approved Name Location Source
PHF5A PHD finger protein 5A 22q13.2 Mapped by PBA pathway
PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) 11q12.2 Mapped by significant region
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 18q11.2 Mapped by significant region
PRPF4 PRP4 pre-mRNA processing factor 4 homolog (yeast) 9q31-q33 Mapped by significant region
CDC40 cell division cycle 40 homolog (S. cerevisiae) 6q22.1 Mapped by PBA pathway
SMNDC1 survival motor neuron domain containing 1 10q23 Mapped by PBA pathway
HSPA8 heat shock 70kDa protein 8 11q24.1 Mapped by significant region
SNRPA small nuclear ribonucleoprotein polypeptide A 19q13.1 Mapped by PBA pathway
BCAS2 breast carcinoma amplified sequence 2 1p13.2 Mapped by PBA pathway
SF3B2 splicing factor 3b, subunit 2, 145kDa 11q13 Mapped by PBA pathway; Mapped by significant region
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 19q13.2-q13.3 Mapped by PBA pathway
SNRPF small nuclear ribonucleoprotein polypeptide F 12q23.1 Mapped by PBA pathway
SNRPG small nuclear ribonucleoprotein polypeptide G 2p13.3 Mapped by PBA pathway
SLU7 SLU7 splicing factor homolog (S. cerevisiae) 5q33.3 Mapped by PBA pathway; Mapped by significant region
SNW1 SNW domain containing 1 14q22.1-q22.3 Mapped by PBA pathway
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 15q26.3 Mapped by PBA pathway
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 20p13 Mapped by PBA pathway
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 19p13.1 Mapped by PBA pathway
SNRPB2 small nuclear ribonucleoprotein polypeptide B 20p12.1 Mapped by PBA pathway
SNRPC small nuclear ribonucleoprotein polypeptide C 6p21 Mapped by PBA pathway
DHX15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 4p15.3 Mapped by CNV; Mapped by PBA pathway
CWC15 CWC15 spliceosome-associated protein homolog (S. cerevisiae) 11q21 Mapped by significant region
HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 13q14.3 Mapped by LD-proxy
EFTUD2 elongation factor Tu GTP binding domain containing 2 17q21.31 Mapped by PBA pathway
SART1 squamous cell carcinoma antigen recognized by T cells 11q13.1 Mapped by significant region
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 22q11.23 Mapped by CNV; Mapped by PBA pathway
SF3A1 splicing factor 3a, subunit 1, 120kDa 22q12.2 Mapped by PBA pathway
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 12q13.1 Mapped by PBA pathway
NCBP1 nuclear cap binding protein subunit 1, 80kDa 9q34.1 Mapped by significant region
SF3B4 splicing factor 3b, subunit 4, 49kDa 1q21.2 Mapped by PBA pathway
SF3B3 splicing factor 3b, subunit 3, 130kDa 16q22 Mapped by PBA pathway
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 14q11 Mapped by PBA pathway
SF3A3 splicing factor 3a, subunit 3, 60kDa 1p Mapped by PBA pathway
SF3A2 splicing factor 3a, subunit 2, 66kDa 19p13.3-p13.2 Mapped by PBA pathway
SRSF8 serine/arginine-rich splicing factor 8 11q22 Mapped by significant region
HSPA6 heat shock 70kDa protein 6 (HSP70B') 1q23.3 Mapped by CNV
TRA2A transformer 2 alpha homolog (Drosophila) 7p15.3 Mapped by CNV; Mapped by significant region
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 12q13.11 Mapped by PBA pathway
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 2q11.2 Mapped by LD-proxy
PRPF18 PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae) 10p12.33 Mapped by PBA pathway
PPIH peptidylprolyl isomerase H (cyclophilin H) 1p34.1 Mapped by PBA pathway
U2AF2 U2 small nuclear RNA auxiliary factor 2 19q13.43 Mapped by PBA pathway
TXNL4A thioredoxin-like 4A 18q23 Mapped by PBA pathway
PRPF6 PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) 20q13.33 Mapped by PBA pathway
U2AF1 U2 small nuclear RNA auxiliary factor 1 21q22.3 Mapped by PBA pathway
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 17q21.31 Mapped by PBA pathway
PRPF8 PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) 17p13.3 Mapped by PBA pathway

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014