ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TRA2A
Symbol Alias	htra-2-alpha, tra2a
Approved Name	transformer 2 alpha homolog (Drosophila)
Location	7p15.3
Position	chr7:23544399-23571660, -
External Links	HGNC: 16645 Entrez Gene: 29896 Ensembl: ENSG00000164548 UCSC: uc003swi.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Lesch[2011]_6	chr7:23010000-26070000 (NCBI Build 35 (hg17))	3060000	7p15.2-7p15.3	Duplication	Paternal (affected)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
7p15	chr7:20900000-28800000	2 (1/1/0)

Gene related GO terms (count: 4)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005634	nucleus	Cellular Component	IDA[9546399]	770
GO:0003723	RNA binding	Molecular Function		104
GO:0000398	mRNA splicing, via spliceosome	Biological Process	IDA[9546399]	54
GO:0000166	nucleotide binding	Molecular Function		73

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03040	Spliceosome	47	After transcription, eukaryotic mRNA precursors contain prot...... After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified. More...

Genes shared at least 5 GO terms with TRA2A (count: 0)

Genes shared at least 2 KEGG pathways with TRA2A (count: 0)

View in gBrowse

Region: chr7:23544399..23571660 View in gBrowse