ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0048471
Name perinuclear region of cytoplasm
Type cellular component
No. of Genes in ADHDgene  99
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 99)

Literature-origin genes (count: 12)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ATXN2 ataxin 2 12q23-q24.1 1(0/0/1) IDA[17097639]
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 7q21 1(0/0/1) ISS
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0) IEA
PARK2 parkin RBR E3 ubiquitin protein ligase 6q25.2-q27 1(1/0/0) IDA[17097639]
SNAP25 synaptosomal-associated protein, 25kDa 20p12-p11.2 21(16/5/0) IEA
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IDA
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 11p11.2 1(0/0/1) IEA
BDNF brain-derived neurotrophic factor 11p14.1 16(8/8/0) ISS
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 22q11.22 1(0/0/1) IEA
MOBP myelin-associated oligodendrocyte basic protein 3p21.33 1(0/0/1) IEA
NOS1 nitric oxide synthase 1 (neuronal) 12q24.22 1(1/0/0) ISS[17027776]
AANAT aralkylamine N-acetyltransferase 17q25.1 1(0/0/1) IDA[11313340]

Genes from other sources Help (count: 87)

Approved Symbol Approved Name Source Evidence[PMID]
RC3H2 ring finger and CCCH-type domains 2 Mapped by significant region IEA
DGAT2 diacylglycerol O-acyltransferase 2 Mapped by significant region ISS
MAP1S microtubule-associated protein 1S Mapped by PBA pathway IDA[12762840]
MAP6 microtubule-associated protein 6 Mapped by significant region IDA[17210638]
PLA2G16 phospholipase A2, group XVI Mapped by significant region IEA
PICALM phosphatidylinositol binding clathrin assembly protein Mapped by significant region ISS
VPS33B vacuolar protein sorting 33 homolog B (yeast) Mapped by LD-proxy IDA[19109425]
SEC23A Sec23 homolog A (S. cerevisiae) Mapped by LD-proxy IEA
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Mapped by PBA pathway ISS
EHD3 EH-domain containing 3 Mapped by CNV IEA
TPPP tubulin polymerization promoting protein Mapped by significant region; Mapped by PBA pathway IDA[15590652]
BSPRY B-box and SPRY domain containing Mapped by significant region IEA
EHD1 EH-domain containing 1 Mapped by significant region IEA
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 Mapped by Literature SNP ISS
SEPT12 septin 12 Mapped by significant region IDA[18047794]
PTCH1 patched 1 Mapped by significant region IDA[11278759]
KRT18 keratin 18 Mapped by PBA pathway IEA
GAK cyclin G associated kinase Mapped by LD-proxy IEA
UNC45A unc-45 homolog A (C. elegans) Mapped by LD-proxy IEA
RAB14 RAB14, member RAS oncogene family Mapped by significant region; Mapped by PBA pathway ISS
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3 Mapped by significant region IDA[18823379]
TYR tyrosinase Mapped by significant region IDA[11092760]
EPHA5 EPH receptor A5 Mapped by CNV; Mapped by significant region IDA[10375373]
PNPLA8 patatin-like phospholipase domain containing 8 Mapped by PBA pathway IEA
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) Mapped by significant region IEA
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa Mapped by CNV IDA[15870280]
STK33 serine/threonine kinase 33 Mapped by Literature SNP IEA
LPXN leupaxin Mapped by significant region IEA
CCDC78 coiled-coil domain containing 78 Mapped by significant region IDA
CLINT1 clathrin interactor 1 Mapped by significant region IEA
CDK5RAP2 CDK5 regulatory subunit associated protein 2 Mapped by significant region IDA[17959831]
PDE2A phosphodiesterase 2A, cGMP-stimulated Mapped by significant region IDA[10375378]
PLN phospholamban Mapped by significant region ISS
FAM168B family with sequence similarity 168, member B Mapped by CNV; Mapped by significant region IEA
NRBP1 nuclear receptor binding protein 1 Mapped by PBA pathway IEA
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase Mapped by significant region IDA[17196169]
GOLGA1 golgin A1 Mapped by significant region IEA
DCTN3 dynactin 3 (p22) Mapped by LD-proxy IDA[9722614]
SPIRE1 spire-type actin nucleation factor 1 Mapped by CNV IEA
TSC2 tuberous sclerosis 2 Mapped by significant region IDA[8806680]
CYFIP1 cytoplasmic FMR1 interacting protein 1 Mapped by significant region ISS
PLD1 phospholipase D1, phosphatidylcholine-specific Mapped by PBA pathway IEA
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12 Mapped by significant region IEA
NF2 neurofibromin 2 (merlin) Mapped by PBA pathway IDA[17210637]
CABP2 calcium binding protein 2 Mapped by significant region IEA
PICK1 protein interacting with PRKCA 1 Mapped by Literature SNP ISS
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 Mapped by CNV IEA
NELL1 NEL-like 1 (chicken) Mapped by CNV IDA
RAB40C RAB40C, member RAS oncogene family Mapped by significant region IEA
TPD52L1 tumor protein D52-like 1 Mapped by significant region IDA[12963375]
PLA2G5 phospholipase A2, group V Mapped by PBA pathway IEA
ACHE acetylcholinesterase (Yt blood group) Mapped by PBA pathway IDA[14766237]
USP2 ubiquitin specific peptidase 2 Mapped by significant region IEA
SORT1 sortilin 1 Mapped by CNV IDA[11331584]
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta Mapped by CNV IEA
SLC39A13 solute carrier family 39 (zinc transporter), member 13 Mapped by LD-proxy ISS[18985159]
TRAPPC2L trafficking protein particle complex 2-like Mapped by significant region IEA
NOX4 NADPH oxidase 4 Mapped by significant region IEA
CYFIP2 cytoplasmic FMR1 interacting protein 2 Mapped by significant region IDA[10449408]
NMRAL1 NmrA-like family domain containing 1 Mapped by significant region IEA
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 Mapped by significant region IEA
KLHL20 kelch-like family member 20 Mapped by significant region IEA
KAT5 K(lysine) acetyltransferase 5 Mapped by significant region IEA
RASD1 RAS, dexamethasone-induced 1 Mapped by significant region IEA
STX7 syntaxin 7 Mapped by significant region; Mapped by PBA pathway IEA
TWF2 twinfilin actin-binding protein 2 Mapped by LD-proxy ISS[12807912]
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 Mapped by significant region IDA[10513816]
AATK apoptosis-associated tyrosine kinase Mapped by LD-proxy IEA
OPTN optineurin Mapped by PBA pathway IEA
OBSL1 obscurin-like 1 Mapped by significant region TAS[17289344]
STK16 serine/threonine kinase 16 Mapped by significant region IEA
GALNT1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) Mapped by significant region IDA[12506059]
STX6 syntaxin 6 Mapped by significant region IDA[10506127]
GSN gelsolin Mapped by significant region; Mapped by PBA pathway IEA
SYT4 synaptotagmin IV Mapped by significant region IEA
ERBB2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 Mapped by LD-proxy IEA
STX4 syntaxin 4 Mapped by CNV IEA
PRDX5 peroxiredoxin 5 Mapped by significant region IDA[10095767]
CALN1 calneuron 1 Mapped by CNV IEA
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 Mapped by significant region IEA
MAP7 microtubule-associated protein 7 Mapped by significant region; Mapped by PBA pathway IEA
NPC1 Niemann-Pick disease, type C1 Mapped by significant region IDA[12554680]
CTGF connective tissue growth factor Mapped by significant region IEA
AXIN1 axin 1 Mapped by significant region IDA[19038973]
SIPA1 signal-induced proliferation-associated 1 Mapped by significant region IEA
CEP250 centrosomal protein 250kDa Mapped by PBA pathway IEA
TLR4 toll-like receptor 4 Mapped by significant region IDA[15027902]