ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	PLA2G16
Previous Symbol	HRASLS3
Symbol Alias	HREV107, H-REV107-1, HREV107-3, MGC118754., AdPLA
Approved Name	phospholipase A2, group XVI
Previous Name	HRAS-like suppressor 3
Name Alias	adipose-specific PLA2
Location	11q12.3
Position	chr11:63341934-63381941, -
External Links	HGNC: 17825 Entrez Gene: 11145 Ensembl: ENSG00000176485 UCSC: uc009you.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 19)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 19)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005575	cellular_component	Cellular Component		98
GO:0005783	endoplasmic reticulum	Cellular Component		100
GO:0004623	phospholipase A2 activity	Molecular Function		10
GO:0005515	protein binding	Molecular Function	IPI[17374643]	910
GO:0008970	phosphatidylcholine 1-acylhydrolase activity	Molecular Function		3
GO:0016021	integral to membrane	Cellular Component		845
GO:0005829	cytosol	Cellular Component		447
GO:0006644	phospholipid metabolic process	Biological Process		59
GO:0036152	phosphatidylethanolamine acyl-chain remodeling	Biological Process		15
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0045786	negative regulation of cell cycle	Biological Process		9
GO:0046474	glycerophospholipid biosynthetic process	Biological Process		30
GO:0016042	lipid catabolic process	Biological Process		32
GO:0036149	phosphatidylinositol acyl-chain remodeling	Biological Process		8
GO:0036150	phosphatidylserine acyl-chain remodeling	Biological Process		10
GO:0036151	phosphatidylcholine acyl-chain remodeling	Biological Process		15
GO:0048471	perinuclear region of cytoplasm	Cellular Component		87
GO:0052739	phosphatidylserine 1-acylhydrolase activity	Molecular Function		1
GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity	Molecular Function		1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PLA2G16 (count: 22)

Gene Symbol	Pathway Count	Pathway List
PLA2G2A	10	endoplasmic reticulum; phospholipase A2 activity; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process; phosphatidylinositol acyl-chain remodeling; phosphatidylserine acyl-chain remodeling; phosphatidylcholine acyl-chain remodeling;
PLA2G10	9	phospholipase A2 activity; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process; phosphatidylinositol acyl-chain remodeling; phosphatidylserine acyl-chain remodeling; phosphatidylcholine acyl-chain remodeling;
PLA2G2D	9	phospholipase A2 activity; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process; phosphatidylinositol acyl-chain remodeling; phosphatidylserine acyl-chain remodeling; phosphatidylcholine acyl-chain remodeling;
PLA2G2E	9	phospholipase A2 activity; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process; phosphatidylinositol acyl-chain remodeling; phosphatidylserine acyl-chain remodeling; phosphatidylcholine acyl-chain remodeling;
PLA2G5	9	phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process; phosphatidylinositol acyl-chain remodeling; phosphatidylserine acyl-chain remodeling; phosphatidylcholine acyl-chain remodeling; perinuclear region of cytoplasm;
PLA2G1B	8	phospholipase A2 activity; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; phosphatidylinositol acyl-chain remodeling; phosphatidylserine acyl-chain remodeling; phosphatidylcholine acyl-chain remodeling;
PLA2G6	8	phospholipase A2 activity; cytosol; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process; phosphatidylcholine acyl-chain remodeling;
LPCAT4	7	integral to membrane; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; phosphatidylserine acyl-chain remodeling; phosphatidylcholine acyl-chain remodeling;
PNPLA8	7	integral to membrane; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; phosphatidylcholine acyl-chain remodeling; perinuclear region of cytoplasm;
PLA2G4B	7	cytosol; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; phosphatidylserine acyl-chain remodeling; phosphatidylcholine acyl-chain remodeling;
PLA2G4C	7	cytosol; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; phosphatidylinositol acyl-chain remodeling; phosphatidylcholine acyl-chain remodeling;
DGAT2	6	endoplasmic reticulum; integral to membrane; phospholipid metabolic process; small molecule metabolic process; glycerophospholipid biosynthetic process; perinuclear region of cytoplasm;
LPCAT1	6	endoplasmic reticulum; integral to membrane; phospholipid metabolic process; small molecule metabolic process; glycerophospholipid biosynthetic process; phosphatidylcholine acyl-chain remodeling;
PLD3	6	protein binding; integral to membrane; phospholipid metabolic process; small molecule metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process;
MBOAT1	6	integral to membrane; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; phosphatidylserine acyl-chain remodeling;
MBOAT2	6	integral to membrane; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; phosphatidylcholine acyl-chain remodeling;
PLA2G3	6	phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process; phosphatidylcholine acyl-chain remodeling;
PNPLA3	5	phospholipase A2 activity; integral to membrane; phospholipid metabolic process; small molecule metabolic process; glycerophospholipid biosynthetic process;
ACHE	5	protein binding; phospholipid metabolic process; small molecule metabolic process; glycerophospholipid biosynthetic process; perinuclear region of cytoplasm;
PLD2	5	protein binding; phospholipid metabolic process; small molecule metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process;
PLD6	5	integral to membrane; phospholipid metabolic process; small molecule metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process;
PLD1	5	phospholipid metabolic process; small molecule metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process; perinuclear region of cytoplasm;

Genes shared at least 2 KEGG pathways with PLA2G16 (count: 0)

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Region: chr11:63341934..63381941 View in gBrowse