ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	TPD52L1
Symbol Alias	D53, hD53
Approved Name	tumor protein D52-like 1
Location	6q22-q23
Position	chr6:125440195-125585553, +
External Links	HGNC: 12006 Entrez Gene: 7164 Ensembl: ENSG00000111907 UCSC: uc003pzu.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
6q22-23	chr6:114600000-139000000	1 (1/0/0)

Gene related GO terms (count: 13)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000086	G2/M transition of mitotic cell cycle	Biological Process	IDA[16112108]	29
GO:0005515	protein binding	Molecular Function	IPI[9484778]	910
GO:0005737	cytoplasm	Cellular Component	IDA[12963375]	690
GO:0006309	apoptotic DNA fragmentation	Biological Process	IDA[14761963]	3
GO:0006917	induction of apoptosis	Biological Process	IDA[14761963]	31
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	Molecular Function	IDA[14761963]	7
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological Process	IDA[14761963]	11
GO:0042803	protein homodimerization activity	Molecular Function	IDA[9484778]	113
GO:0042802	identical protein binding	Molecular Function	IPI[9484778]	70
GO:0046330	positive regulation of JNK cascade	Biological Process	IDA[14761963]	12
GO:0043406	positive regulation of MAP kinase activity	Biological Process	IDA[14761963]	10
GO:0048471	perinuclear region of cytoplasm	Cellular Component	IDA[12963375]	87
GO:0046982	protein heterodimerization activity	Molecular Function	IDA[9484778]	68

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TPD52L1 (count: 12)

Gene Symbol	Pathway Count	Pathway List
BNIP3	7	protein binding; cytoplasm; apoptotic DNA fragmentation; induction of apoptosis; protein homodimerization activity; identical protein binding; protein heterodimerization activity;
PYCARD	7	protein binding; cytoplasm; induction of apoptosis; cysteine-type endopeptidase activator activity involved in apoptotic process; activation of cysteine-type endopeptidase activity involved in apoptotic process; protein homodimerization activity; positive regulation of JNK cascade;
VEGFA	6	protein binding; cytoplasm; protein homodimerization activity; identical protein binding; positive regulation of MAP kinase activity; protein heterodimerization activity;
PAFAH1B1	5	G2/M transition of mitotic cell cycle; protein binding; cytoplasm; protein homodimerization activity; perinuclear region of cytoplasm;
ADRA2A	5	protein binding; cytoplasm; protein homodimerization activity; positive regulation of MAP kinase activity; protein heterodimerization activity;
BAD	5	protein binding; induction of apoptosis; cysteine-type endopeptidase activator activity involved in apoptotic process; activation of cysteine-type endopeptidase activity involved in apoptotic process; protein heterodimerization activity;
ERBB2	5	protein binding; identical protein binding; positive regulation of MAP kinase activity; perinuclear region of cytoplasm; protein heterodimerization activity;
IL12B	5	protein binding; cytoplasm; protein homodimerization activity; identical protein binding; protein heterodimerization activity;
MAP3K11	5	protein binding; cytoplasm; protein homodimerization activity; identical protein binding; positive regulation of JNK cascade;
MAP3K5	5	protein binding; cysteine-type endopeptidase activator activity involved in apoptotic process; activation of cysteine-type endopeptidase activity involved in apoptotic process; protein homodimerization activity; identical protein binding;
SNCA	5	protein binding; cytoplasm; activation of cysteine-type endopeptidase activity involved in apoptotic process; identical protein binding; perinuclear region of cytoplasm;
TYR	5	protein binding; cytoplasm; protein homodimerization activity; perinuclear region of cytoplasm; protein heterodimerization activity;

Genes shared at least 2 KEGG pathways with TPD52L1 (count: 0)

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Region: chr6:125440195..125585553 View in gBrowse