ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005783
Name endoplasmic reticulum
Type Cellular Component
No. of Genes in ADHDgene  100
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 100)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ATP11A ATPase, class VI, type 11A 13q34 1(0/1/0)
PARK2 parkinson protein 2, E3 ubiquitin protein ligase (parkin) 6q25.2-q27 1(1/0/0)
STS steroid sulfatase (microsomal), isozyme S Xp22.32 3(2/1/0) TAS[2668275]
ELOVL6 ELOVL fatty acid elongase 6 4q25 1(0/0/1)
OPRM1 opioid receptor, mu 1 6q24-q25 1(1/0/0) TAS[9242668]
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 22q11.1-q11.2 1(0/1/0) TAS[2117645]
DHCR7 7-dehydrocholesterol reductase 11q13.4 1(0/0/1) IDA[9878250]

Genes from other sources Help (count: 93)

Approved Symbol Approved Name Source Evidence[PMID]
PLA2G16 phospholipase A2, group XVI Mapped by significant region
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) Mapped by PBA pathway IDA[12237308]
DSE dermatan sulfate epimerase Mapped by significant region IDA[10679095]
SRD5A3 steroid 5 alpha-reductase 3 Mapped by LD-proxy
NCK1 NCK adaptor protein 1 Mapped by PBA pathway
DDRGK1 DDRGK domain containing 1 Mapped by CNV
KIAA0368 KIAA0368 Mapped by significant region IDA[15496406]
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) Mapped by PBA pathway TAS[9501016]
RTN4R reticulon 4 receptor Mapped by CNV
BET3L BET3 like (S. cerevisiae) Mapped by significant region
NCK2 NCK adaptor protein 2 Mapped by PBA pathway
SREBF1 sterol regulatory element binding transcription factor 1 Mapped by significant region IDA[12202038]
TMED2 transmembrane emp24 domain trafficking protein 2 Mapped by CNV IDA[12237308]
STX18 syntaxin 18 Mapped by PBA pathway TAS[10788491]
SLC39A6 solute carrier family 39 (zinc transporter), member 6 Mapped by significant region
PANX1 pannexin 1 Mapped by significant region IDA[16908669]
DGAT2 diacylglycerol O-acyltransferase 2 Mapped by significant region IDA[14521909]
KLHL14 kelch-like 14 (Drosophila) Mapped by significant region IDA[19535332]
PDIA3 protein disulfide isomerase family A, member 3 Mapped by PBA pathway TAS[16130169]
PLN phospholamban Mapped by significant region
GLYATL2 glycine-N-acyltransferase-like 2 Mapped by significant region
VPREB3 pre-B lymphocyte 3 Mapped by CNV NAS[10702669]
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 Mapped by CNV IDA[15764604]
ATL3 atlastin GTPase 3 Mapped by significant region IDA[18270207]
CRIPAK cysteine-rich PAK1 inhibitor Mapped by PBA pathway IDA[16278681]
PDIA6 protein disulfide isomerase family A, member 6 Mapped by significant region TAS[16130169]
MAN1A1 mannosidase, alpha, class 1A, member 1 Mapped by significant region TAS[8223597]
PDILT protein disulfide isomerase-like, testis expressed Mapped by significant region
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 Mapped by LD-proxy; Mapped by literature SNP IDA[18556656]
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 Mapped by CNV NAS[8648241]
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 Mapped by significant region NAS[212064]
LPCAT1 lysophosphatidylcholine acyltransferase 1 Mapped by LD-proxy
LTC4S leukotriene C4 synthase Mapped by CNV IDA[19233132]
SYVN1 synovial apoptosis inhibitor 1, synoviolin Mapped by significant region
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 Mapped by LD-proxy TAS[1898728]
NPC1 Niemann-Pick disease, type C1 Mapped by significant region IDA[12554680]
REEP1 receptor accessory protein 1 Mapped by CNV
KIF1C kinesin family member 1C Mapped by PBA pathway TAS[9685376]
FKTN fukutin Mapped by significant region IDA[18808525]
MOGAT2 monoacylglycerol O-acyltransferase 2 Mapped by significant region IDA[14966132]
ATP10A ATPase, class V, type 10A Mapped by CNV; Mapped by significant region
FKBP2 FK506 binding protein 2, 13kDa Mapped by significant region TAS[1713687]
CLCC1 chloride channel CLIC-like 1 Mapped by CNV
PDZD2 PDZ domain containing 2 Mapped by significant region ISS[12671685]
SRPR signal recognition particle receptor (docking protein) Mapped by significant region TAS[2827661]
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 Mapped by LD-proxy; Mapped by literature SNP IDA[18556656]
DHRS1 dehydrogenase/reductase (SDR family) member 1 Mapped by significant region
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) Mapped by PBA pathway IDA[15029241]
CANX calnexin Mapped by CNV
CUBN cubilin (intrinsic factor-cobalamin receptor) Mapped by CNV
RTN3 reticulon 3 Mapped by significant region
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 Mapped by significant region
ZW10 ZW10, kinetochore associated, homolog (Drosophila) Mapped by PBA pathway; Mapped by significant region IDA[15029241]
AQP11 aquaporin 11 Mapped by significant region
UNC93B1 unc-93 homolog B1 (C. elegans) Mapped by significant region
PTP4A1 protein tyrosine phosphatase type IVA, member 1 Mapped by significant region
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) Mapped by PBA pathway; Mapped by significant region IDA[18505924]
MR1 major histocompatibility complex, class I-related Mapped by significant region
TRAPPC2L trafficking protein particle complex 2-like Mapped by significant region
PYCARD PYD and CARD domain containing Mapped by CNV
RTN4 reticulon 4 Mapped by CNV NAS[11126360]
FAM57B family with sequence similarity 57, member B Mapped by CNV
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 Mapped by significant region
ELOVL7 ELOVL fatty acid elongase 7 Mapped by CNV
KCNRG potassium channel regulator Mapped by LD-proxy
PIGL phosphatidylinositol glycan anchor biosynthesis, class L Mapped by significant region
TAPBP TAP binding protein (tapasin) Mapped by LD-proxy TAS[9238042]
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) Mapped by PBA pathway IDA[9211930]
FCRLB Fc receptor-like B Mapped by CNV
STX5 syntaxin 5 Mapped by significant region
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) Mapped by PBA pathway
ZP2 zona pellucida glycoprotein 2 (sperm receptor) Mapped by significant region
LRP5 low density lipoprotein receptor-related protein 5 Mapped by CNV; Mapped by significant region
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 Mapped by significant region
PDE2A phosphodiesterase 2A, cGMP-stimulated Mapped by significant region
CES2 carboxylesterase 2 Mapped by PBA pathway TAS[9144407]
TRAPPC4 trafficking protein particle complex 4 Mapped by significant region
HYOU1 hypoxia up-regulated 1 Mapped by significant region TAS[9020069]
STIM2 stromal interaction molecule 2 Mapped by CNV IDA[18160041]
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 Mapped by significant region IDA[11300766]
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Mapped by significant region IDA[16223484]; IMP[11943137]; TAS[16130169]
SQSTM1 sequestosome 1 Mapped by CNV
BACE1 beta-site APP-cleaving enzyme 1 Mapped by significant region
CCDC88A coiled-coil domain containing 88A Mapped by PBA pathway IDA[15882442]
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 Mapped by significant region
TM7SF2 transmembrane 7 superfamily member 2 Mapped by significant region TAS[9878250]
CTSC cathepsin C Mapped by significant region
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) Mapped by significant region NAS[7656593]
PLCD4 phospholipase C, delta 4 Mapped by significant region
THY1 Thy-1 cell surface antigen Mapped by significant region
ZFAND2B zinc finger, AN1-type domain 2B Mapped by significant region
MAP3K5 mitogen-activated protein kinase kinase kinase 5 Mapped by LD-proxy; Mapped by significant region
FAM134A family with sequence similarity 134, member A Mapped by significant region

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014