ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005102
Name receptor binding
Type molecular function
No. of Genes in ADHDgene  64
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 64)

Literature-origin genes (count: 10)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
NXPH1 neurexophilin 1 7p22 1(0/1/0) IEA
GDNF glial cell derived neurotrophic factor 5p13.1-p12 2(1/1/0) TAS[10829012]
NTF3 neurotrophin 3 12p13 4(1/3/0) TAS[2236018]
LPL lipoprotein lipase 8p22 1(0/0/1) IPI[10085125]
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 5p15.3 70(43/26/1) IEA
ARRB2 arrestin, beta 2 17p13 1(1/0/0) IPI[18604210]
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 17q12 1(0/1/0) IEA
NRXN1 neurexin 1 2p16.3 1(0/1/0) ISS
NPPC natriuretic peptide C 2q37.1 1(0/1/0) IPI[1660465]
CNTFR ciliary neurotrophic factor receptor 9p13 1(1/0/0) IPI[12707266]

Genes from other sources Help (count: 54)

Approved Symbol Approved Name Source Evidence[PMID]
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D Mapped by significant region IDA[11254688]
CTNND1 catenin (cadherin-associated protein), delta 1 Mapped by significant region IPI[19332538]
LAMA3 laminin, alpha 3 Mapped by significant region IEA
C5 complement component 5 Mapped by significant region TAS[9590258]
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) Mapped by CNV IPI[12782713]
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 Mapped by significant region IPI
ANGPTL2 angiopoietin-like 2 Mapped by significant region IEA
FYB FYN binding protein Mapped by significant region TAS[10747096]
ANGPTL5 angiopoietin-like 5 Mapped by significant region IEA
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase Mapped by CNV IEA
TNC tenascin C Mapped by significant region IEA
CLCF1 cardiotrophin-like cytokine factor 1 Mapped by significant region IPI[15272019]
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 Mapped by significant region TAS[8391931]
PTPRD protein tyrosine phosphatase, receptor type, D Mapped by CNV ISS
TRDN triadin Mapped by significant region IEA
TIGIT T cell immunoreceptor with Ig and ITIM domains Mapped by LD-proxy IPI[19011627]
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 Mapped by significant region IPI[16456542]
MPV17L MPV17 mitochondrial membrane protein-like Mapped by CNV; Mapped by significant region IPI
NPY neuropeptide Y Mapped by CNV; Mapped by significant region TAS[8132547]
PLA2G1B phospholipase A2, group IB (pancreas) Mapped by PBA pathway IDA[1918029]; IPI[7721806]
MFAP4 microfibrillar-associated protein 4 Mapped by significant region IEA
UFD1L ubiquitin fusion degradation 1 like (yeast) Mapped by CNV IEA
C1QTNF2 C1q and tumor necrosis factor related protein 2 Mapped by significant region IEA
MAP7 microtubule-associated protein 7 Mapped by significant region; Mapped by PBA pathway ISS
PECR peroxisomal trans-2-enoyl-CoA reductase Mapped by significant region IPI[11669066]
CADM1 cell adhesion molecule 1 Mapped by significant region IPI[15811952]; ISS[12826663]
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal Mapped by significant region IPI
AMACR alpha-methylacyl-CoA racemase Mapped by significant region IPI[11060344]
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 Mapped by significant region TAS[7913952]
NMU neuromedin U Mapped by LD-proxy TAS[10811630]
F7 coagulation factor VII (serum prothrombin conversion accelerator) Mapped by CNV IEA
PGR progesterone receptor Mapped by significant region IPI[12771131]
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 Mapped by significant region TAS[10074428]
NCK1 NCK adaptor protein 1 Mapped by PBA pathway IPI[12110186]
CXCL12 chemokine (C-X-C motif) ligand 12 Mapped by PBA pathway TAS[10438529]
CNTNAP2 contactin associated protein-like 2 Mapped by CNV IEA
TNR tenascin R Mapped by significant region IEA
RASA1 RAS p21 protein activator (GTPase activating protein) 1 Mapped by PBA pathway IPI[2157284]
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 Mapped by PBA pathway IPI[14701856]
CNTNAP4 contactin associated protein-like 4 Mapped by significant region IEA
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 Mapped by PBA pathway IDA[12466272]
GRP gastrin-releasing peptide Mapped by significant region NAS[3027901]
MLYCD malonyl-CoA decarboxylase Mapped by CNV; Mapped by significant region IPI
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 Mapped by significant region TAS[9434163]
NTN3 netrin 3 Mapped by significant region IEA
CRTAM cytotoxic and regulatory T cell molecule Mapped by significant region IPI[15811952]
PAOX polyamine oxidase (exo-N4-amino) Mapped by CNV IPI
PRDX5 peroxiredoxin 5 Mapped by significant region IPI
GLG1 golgi glycoprotein 1 Mapped by significant region TAS[7531823]
INHA inhibin, alpha Mapped by significant region IPI[9032295]
PICK1 protein interacting with PRKCA 1 Mapped by Literature SNP ISS
LAMA2 laminin, alpha 2 Mapped by CNV; Mapped by significant region IEA
BAAT bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) Mapped by significant region IPI
PANX1 pannexin 1 Mapped by significant region IPI[17036048]