ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	INHA
Approved Name	inhibin, alpha
Location	2q35
Position	chr2:220433884-220440435, 1
External Links	HGNC: 6065 Entrez Gene: 3623 Ensembl: ENSG00000123999 UCSC: uc002vmk.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
2q35	chr2:215300000-221500000	1 (1/0/0)

Gene related GO terms (count: 35)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 35)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0045650	negative regulation of macrophage differentiation	biological process	TAS[12456957]	1
GO:0045077	negative regulation of interferon-gamma biosynthetic process	biological process	TAS[12456957]	1
GO:0046881	positive regulation of follicle-stimulating hormone secretion	biological process	TAS[12456957]	1
GO:0001541	ovarian follicle development	biological process	NAS[9166111]	4
GO:0001917	photoreceptor inner segment	cellular component	IEA	5
GO:0030154	cell differentiation	biological process	TAS[12456957]	61
GO:0008584	male gonad development	biological process	IEA	10
GO:0001501	skeletal system development	biological process	TAS[10865214]	17
GO:0007050	cell cycle arrest	biological process	TAS[12456957]	28
GO:0043512	inhibin A complex	cellular component	IDA[7890768]	1
GO:0007399	nervous system development	biological process	NAS[10320815]	60
GO:0045578	negative regulation of B cell differentiation	biological process	TAS[12456957]	2
GO:0001750	photoreceptor outer segment	cellular component	IEA	7
GO:0042326	negative regulation of phosphorylation	biological process	TAS[12456957]	4
GO:0005515	protein binding	molecular function	IPI[2575216]; IPI[10746731]	1015
GO:0008083	growth factor activity	molecular function	TAS[12324653]	28
GO:0030218	erythrocyte differentiation	biological process	NAS[1310063]	4
GO:0007165	signal transduction	biological process	TAS[3267209]	189
GO:0042541	hemoglobin biosynthetic process	biological process	IDA[1310063]	1
GO:0005125	cytokine activity	molecular function	TAS[12456957]	20
GO:0005576	extracellular region	cellular component	TAS[12456957]	267
GO:0046882	negative regulation of follicle-stimulating hormone secretion	biological process	NAS[3267209]	1
GO:0034673	inhibin-betaglycan-ActRII complex	cellular component	IDA[10746731]	1
GO:0009605	response to external stimulus	biological process	TAS[10320815]	1
GO:0046982	protein heterodimerization activity	molecular function	IEA	73
GO:0006917	induction of apoptosis	biological process	IDA[8267637]	35
GO:0051726	regulation of cell cycle	biological process	IDA[9032295]	10
GO:0045786	negative regulation of cell cycle	biological process	TAS[12456957]	9
GO:0005102	receptor binding	molecular function	IPI[9032295]	64
GO:0005179	hormone activity	molecular function	TAS[12456957]	7
GO:0007166	cell surface receptor signaling pathway	biological process	TAS[12456957]	36
GO:0034711	inhibin binding	molecular function	IEA	1
GO:0007267	cell-cell signaling	biological process	TAS[12456957]	41
GO:0043025	neuronal cell body	cellular component	IEA	56
GO:0042127	regulation of cell proliferation	biological process	IDA[9032295]	22

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with INHA (count: 15)

Gene Symbol	Pathway Count	Pathway List
VEGFA	7	ovarian follicle development; nervous system development; protein binding; growth factor activity; cytokine activity; extracellular region; protein heterodimerization activity;
CLCF1	7	protein binding; growth factor activity; cytokine activity; extracellular region; protein heterodimerization activity; receptor binding; cell surface receptor signaling pathway;
NTF3	6	nervous system development; growth factor activity; signal transduction; extracellular region; receptor binding; cell-cell signaling;
FGF9	5	male gonad development; growth factor activity; signal transduction; extracellular region; cell-cell signaling;
TGFBR1	5	skeletal system development; cell cycle arrest; protein binding; signal transduction; induction of apoptosis;
IGF2	5	skeletal system development; protein binding; growth factor activity; extracellular region; hormone activity;
TSC2	5	cell cycle arrest; protein binding; protein heterodimerization activity; regulation of cell cycle; neuronal cell body;
IL12B	5	cell cycle arrest; protein binding; growth factor activity; cytokine activity; protein heterodimerization activity;
ERBB2	5	nervous system development; protein binding; signal transduction; protein heterodimerization activity; cell surface receptor signaling pathway;
GDNF	5	nervous system development; growth factor activity; signal transduction; extracellular region; receptor binding;
PTPRK	5	photoreceptor outer segment; protein binding; signal transduction; negative regulation of cell cycle; neuronal cell body;
TXN	5	protein binding; signal transduction; extracellular region; cell-cell signaling; neuronal cell body;
MIF	5	protein binding; cytokine activity; extracellular region; receptor binding; cell surface receptor signaling pathway;
FGF3	5	protein binding; growth factor activity; signal transduction; extracellular region; cell-cell signaling;
TNFSF8	5	signal transduction; cytokine activity; induction of apoptosis; receptor binding; cell-cell signaling;

Genes shared at least 2 KEGG pathways with INHA (count: 0)

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Region: chr2:220433884..220440435 View in gBrowse