ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PECR
Symbol Alias	HSA250303, TERP, SDR29C1
Approved Name	peroxisomal trans-2-enoyl-CoA reductase
Name Alias	short chain dehydrogenase/reductase family 29C, member 1
Location	2q35
Position	chr2:216861052-216947678, -
External Links	HGNC: 18281 Entrez Gene: 55825 Ensembl: ENSG00000115425 UCSC: uc002vft.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
2q35	chr2:215300000-221500000	1 (1/0/0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity	Molecular Function	IDA[16546181]	1
GO:0033306	phytol metabolic process	Biological Process	IDA[16546181]	2
GO:0043231	intracellular membrane-bounded organelle	Cellular Component		62
GO:0055114	oxidation-reduction process	Biological Process	IDA[16546181]	15
GO:0000166	nucleotide binding	Molecular Function		73
GO:0005102	receptor binding	Molecular Function	IPI[11669066]	61
GO:0005739	mitochondrion	Cellular Component		183
GO:0005777	peroxisome	Cellular Component	IDA[11669066]	15
GO:0005778	peroxisomal membrane	Cellular Component	ISS[10811639]	8
GO:0006633	fatty acid biosynthetic process	Biological Process		16
GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity	Molecular Function	IDA[11669066]	1

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04146	Peroxisome	9	Peroxisomes are essential organelles that play a key role in...... Peroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ether lipids and free radical detoxification. The biogenesis of peroxisomes starts with the early peroxins PEX3, PEX16 and PEX19 and proceeds via several steps. The import of membrane proteins into peroxisomes needs PEX19 for recognition, targeting and insertion via docking at PEX3. Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane. Peroxisomes' deficiencies lead to severe and often fatal inherited peroxisomal disorders (PD). PDs are usually classified in two groups. The first group is disorders of peroxisome biogenesis which include Zellweger syndrome, and the second group is single peroxisomal enzyme deficiencies. More...
hsa01040	Biosynthesis of unsaturated fatty acids	5

Genes shared at least 5 GO terms with PECR (count: 0)

Genes shared at least 2 KEGG pathways with PECR (count: 1)

Gene Symbol	Pathway Count	Pathway List
BAAT	2	Peroxisome; Biosynthesis of unsaturated fatty acids;

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Region: chr2:216861052..216947678 View in gBrowse