ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PTPRD
Symbol Alias	PTPD, HPTP
Approved Name	protein tyrosine phosphatase, receptor type, D
Location	9p24.1-p23
Position	chr9:8314246-10612723, -
External Links	HGNC: 9668 Entrez Gene: 5789 Ensembl: ENSG00000153707 UCSC: uc003zkk.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 4)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_119	chr9:9084805-9178865 (NCBI Build 35 (hg17))	94061	9p23	Deletion (hemizygous)	Maternal
CNV_Elia[2010]_116	chr9:10160101-10423023 (NCBI Build 35 (hg17))	262923	9p23	Deletion (hemizygous)	Maternal
CNV_Elia[2010]_115	chr9:9985938-10020458 (NCBI Build 35 (hg17))	34521	9p23	Deletion (hemizygous)	Paternal
CNV_Elia[2010]_129	chr9:9168137-10067180 (NCBI Build 35 (hg17))	899044	9p23	Deletion (hemizygous)	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	Molecular Function	TAS[7896816]	5
GO:0005887	integral to plasma membrane	Cellular Component	TAS[7896816]	220
GO:0006470	protein dephosphorylation	Biological Process	TAS[7896816]	18
GO:0005102	receptor binding	Molecular Function		61
GO:0005515	protein binding	Molecular Function	IPI[12570871]	910
GO:0030182	neuron differentiation	Biological Process		9
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	Biological Process	TAS[7896816]	2
GO:0007157	heterophilic cell-cell adhesion	Biological Process		11
GO:0006796	phosphate-containing compound metabolic process	Biological Process	NAS[7896816]	3
GO:0097105	presynaptic membrane assembly	Biological Process		3
GO:0050839	cell adhesion molecule binding	Molecular Function		9
GO:0050775	positive regulation of dendrite morphogenesis	Biological Process		2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PTPRD (count: 1)

Gene Symbol	Pathway Count	Pathway List
NRXN1	6	integral to plasma membrane; receptor binding; protein binding; heterophilic cell-cell adhesion; presynaptic membrane assembly; cell adhesion molecule binding;

Genes shared at least 2 KEGG pathways with PTPRD (count: 0)

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Region: chr9:8314246..10612723 View in gBrowse