ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TIGIT
Previous Symbol	VSIG9, VSTM3
Symbol Alias	FLJ39873, DKFZp667A205
Approved Name	T cell immunoreceptor with Ig and ITIM domains
Previous Name	V-set and immunoglobulin domain containing 9, "V-set and transmembrane domain containing 3"
Location	3q13.31
Position	chr3:113995760-114029135, +
External Links	HGNC: 26838 Entrez Gene: 201633 Ensembl: ENSG00000181847 UCSC: uc003ebg.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation
rs4682534	Chr3:114034098(Fwd)	downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0032695	negative regulation of interleukin-12 production	Biological Process	IMP[19011627]	2
GO:0032733	positive regulation of interleukin-10 production	Biological Process	IMP[19011627]	4
GO:0050868	negative regulation of T cell activation	Biological Process	IDA[19011627]; IMP[19011627]	1
GO:0005102	receptor binding	Molecular Function	IPI[19011627]	61
GO:0005515	protein binding	Molecular Function		910
GO:0005886	plasma membrane	Cellular Component		772
GO:0009986	cell surface	Cellular Component	IDA[19011627]	70
GO:0016021	integral to membrane	Cellular Component		845

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TIGIT (count: 1)

Gene Symbol	Pathway Count	Pathway List
NRXN1	5	receptor binding; protein binding; plasma membrane; cell surface; integral to membrane;

Genes shared at least 2 KEGG pathways with TIGIT (count: 0)

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Region: chr3:113995760..114029135 View in gBrowse