ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0043025
Name neuronal cell body
Type cellular component
No. of Genes in ADHDgene  56
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 56)

Literature-origin genes (count: 17)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
CPLX2 complexin 2 5q35.2 2(1/0/1) IEA
CPLX1 complexin 1 4p16.3 1(1/0/0) IEA
SNPH syntaphilin 20p13 1(1/0/0) IEA
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 20q13.33 7(4/3/0) ISS
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 7p12.1 6(5/1/0) IEA
NRSN1 neurensin 1 6p22.1 1(1/0/0) ISS
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 1(1/0/0) IEA
KCNIP4 Kv channel interacting protein 4 4p15.32 1(1/0/0) IEA
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 17q12 1(0/1/0) IEA
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 15q24 1(0/1/0) ISS
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 5p13 2(1/1/0) IEA
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2q12 1(1/0/0) IEA
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 10q25 2(0/2/0) IEA
DRD4 dopamine receptor D4 11p15.5 67(49/18/0) IEA
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 5p15.3 70(43/26/1) IDA[12958153]
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 12p13.3 3(0/3/0) IEA
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0) IEA

Genes from other sources Help (count: 39)

Approved Symbol Approved Name Source Evidence[PMID]
SPTBN2 spectrin, beta, non-erythrocytic 2 Mapped by significant region IEA
NCAM1 neural cell adhesion molecule 1 Mapped by significant region IEA
UBXN1 UBX domain protein 1 Mapped by significant region IEA
P2RX3 purinergic receptor P2X, ligand-gated ion channel, 3 Mapped by significant region IEA
RTN4 reticulon 4 Mapped by CNV IEA
DIXDC1 DIX domain containing 1 Mapped by significant region IBA
STRN3 striatin, calmodulin binding protein 3 Mapped by significant region ISS
KLHL14 kelch-like family member 14 Mapped by significant region IEA
SORT1 sortilin 1 Mapped by CNV IEA
CANX calnexin Mapped by CNV IEA
DENND1A DENN/MADD domain containing 1A Mapped by significant region IEA
TSC2 tuberous sclerosis 2 Mapped by significant region IEA
GHR growth hormone receptor Mapped by CNV; Mapped by significant region IEA
ARG1 arginase 1 Mapped by significant region IEA
KLHL1 kelch-like family member 1 Mapped by CNV IEA
ADORA2A adenosine A2a receptor Mapped by CNV IEA
CAMK2D calcium/calmodulin-dependent protein kinase II delta Mapped by CNV IEA
FABP7 fatty acid binding protein 7, brain Mapped by significant region IEA
MYO10 myosin X Mapped by significant region IEA
PTPRK protein tyrosine phosphatase, receptor type, K Mapped by CNV; Mapped by significant region IEA
KCNIP1 Kv channel interacting protein 1 Mapped by Literature SNP IEA
ILK integrin-linked kinase Mapped by CNV IEA
CYBA cytochrome b-245, alpha polypeptide Mapped by significant region IEA
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1 Mapped by CNV IEA
TMPRSS5 transmembrane protease, serine 5 Mapped by significant region IEA
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Mapped by significant region IDA[17658481]
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 Mapped by PBA pathway IEA
PMM2 phosphomannomutase 2 Mapped by significant region IEA
OMP olfactory marker protein Mapped by significant region IEA
EPHA5 EPH receptor A5 Mapped by CNV; Mapped by significant region IDA[10375373]
TXN thioredoxin Mapped by significant region IEA
SKOR1 SKI family transcriptional corepressor 1 Mapped by LD-proxy IDA[17292623]
KATNB1 katanin p80 (WD repeat containing) subunit B 1 Mapped by PBA pathway IEA
P2RX6 purinergic receptor P2X, ligand-gated ion channel, 6 Mapped by CNV IEA
MAP1S microtubule-associated protein 1S Mapped by PBA pathway ISS[15528209]
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Mapped by PBA pathway IEA
CNTNAP2 contactin associated protein-like 2 Mapped by CNV ISS
INHA inhibin, alpha Mapped by significant region IEA
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 Mapped by LD-proxy IEA