ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NRSN1
Previous Symbol	VMP
Symbol Alias	p24
Approved Name	neurensin 1
Previous Name	vesicular membrane protein p24
Location	6p22.1
Position	chr6:24126350-24156424, +
External Links	HGNC: 17881 Entrez Gene: 140767 Ensembl: ENSG00000152954 UCSC: uc010jpq.1
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin; Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Couto JM, 2009	2 SNPs in this gene were significantly associated with ADHD.	Significant

Gene related SNPs (count: 5)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs3829810	Chr6:24146672(Fwd)	3_prime_UTR_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1(1/0/0)
rs3178	Chr6:24147572(Fwd)	3_prime_UTR_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1(1/0/0)

rs_ID	Location	Functional Annotation
rs3857540	Chr6:24158542(Fwd)	downstream_gene_variant
rs10946675	Chr6:24141920(Fwd)	downstream_gene_variant; intron_variant; nc_transcript_variant
rs1053047	Chr6:24147483(Fwd)	3_prime_UTR_variant; downstream_gene_variant; intron_variant; nc_transcript_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0030133	transport vesicle	Cellular Component	TAS[12463420]	4
GO:0016023	cytoplasmic membrane-bounded vesicle	Cellular Component		16
GO:0043005	neuron projection	Cellular Component		35
GO:0030426	growth cone	Cellular Component		20
GO:0043025	neuronal cell body	Cellular Component		51
GO:0016021	integral to membrane	Cellular Component		845
GO:0007399	nervous system development	Biological Process		54

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NRSN1 (count: 0)

Genes shared at least 2 KEGG pathways with NRSN1 (count: 0)

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Region: chr6:24126350..24156424 View in gBrowse