ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0045087
Name innate immune response
Type Biological Process
No. of Genes in ADHDgene  54
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 54)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TRIM32 tripartite motif containing 32 9q33.1 1(0/0/1) TAS[16175175]
MAP2K3 mitogen-activated protein kinase kinase 3 17q11.2 1(0/1/0)

Genes from other sources Help (count: 52)

Approved Symbol Approved Name Source Evidence[PMID]
UBC ubiquitin C Mapped by CNV
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) Mapped by significant region
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) Mapped by LD-proxy
MAVS mitochondrial antiviral signaling protein Mapped by CNV IMP[19631370]
COLEC12 collectin sub-family member 12 Mapped by CNV TAS[11564734]
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 Mapped by significant region
SYK spleen tyrosine kinase Mapped by significant region
UNC93B1 unc-93 homolog B1 (C. elegans) Mapped by significant region
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 Mapped by significant region
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mapped by significant region
C5 complement component 5 Mapped by significant region
UBE2L6 ubiquitin-conjugating enzyme E2L 6 Mapped by significant region
NLRP10 NLR family, pyrin domain containing 10 Mapped by CNV
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 Mapped by significant region
CORO1A coronin, actin binding protein, 1A Mapped by CNV NAS[17341475]
TXN thioredoxin Mapped by significant region
VNN1 vanin 1 Mapped by significant region ISS[14966568]
IRF7 interferon regulatory factor 7 Mapped by LD-proxy
MAPK9 mitogen-activated protein kinase 9 Mapped by CNV
NLRX1 NLR family member X1 Mapped by significant region
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 Mapped by significant region
PRKD1 protein kinase D1 Mapped by significant region
MASP2 mannan-binding lectin serine peptidase 2 Mapped by literature SNP
DAK dihydroxyacetone kinase 2 homolog (S. cerevisiae) Mapped by significant region
PANX1 pannexin 1 Mapped by significant region
PYCARD PYD and CARD domain containing Mapped by CNV
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 Mapped by LD-proxy
ATG9A ATG9 autophagy related 9 homolog A (S. cerevisiae) Mapped by significant region
C9 complement component 9 Mapped by significant region
RIPK3 receptor-interacting serine-threonine kinase 3 Mapped by significant region
PIK3C3 phosphoinositide-3-kinase, class 3 Mapped by significant region
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) Mapped by CNV; Mapped by significant region
PYDC1 PYD (pyrin domain) containing 1 Mapped by CNV IDA[12656673]
ATG5 ATG5 autophagy related 5 homolog (S. cerevisiae) Mapped by CNV
CYBA cytochrome b-245, alpha polypeptide Mapped by significant region IMP[2243141]
TLR4 toll-like receptor 4 Mapped by significant region TAS[15356140]
HERC5 hect domain and RLD 5 Mapped by CNV
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein Mapped by significant region
TRIM5 tripartite motif containing 5 Mapped by CNV
MAP3K5 mitogen-activated protein kinase kinase kinase 5 Mapped by LD-proxy; Mapped by significant region
FADD Fas (TNFRSF6)-associated via death domain Mapped by significant region
RNF125 ring finger protein 125 Mapped by significant region
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) Mapped by CNV
C6 complement component 6 Mapped by significant region
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 Mapped by significant region
PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide Mapped by CNV TAS[17290298]
C7 complement component 7 Mapped by significant region
NCF2 neutrophil cytosolic factor 2 Mapped by significant region TAS[7938008]
UBB ubiquitin B Mapped by significant region
MAPK7 mitogen-activated protein kinase 7 Mapped by significant region

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014